Infectious diseases, along with cancers, are among the main causes of death among
humans worldwide. The production of therapeutic proteins for treating diseases at large …

Escherichia coli is the most widely used heterologous protein expression system. However,
this system remains a challenge due to the low solubility of proteins, insufficient yield, and …

The baculovirus expression vector system (BEVS) platform has become an established
manufacturing platform for the production of viral vaccines and gene therapy vectors. Nine …

Inactivated and live attenuated vaccines have improved human life and significantly reduced
morbidity and mortality of several human infectious diseases. However, these vaccines have …

The last big outbreaks of Ebola fever in Africa, the thousands of avian influenza outbreaks
across Europe, Asia, North America and Africa, the emergence of monkeypox virus in …

Nucleotide excision repair (NER) is essential for removing many types of DNA lesions from
the genome, yet the mechanisms of NER in humans remain poorly understood. This review …

ABSTRACT HPV vaccine hesitancy in Asia is unique compared to Western countries due to
multidimensional social-cultural norms that influence beliefs regarding vaccination. Reviews …

Vaccines pave the way out of the SARS-CoV-2 pandemic. Besides mRNA and adenoviral
vector vaccines, effective protein-based vaccines are needed for immunization against …

Baculovirus Autographa californica multiple nucleopolyhedrovirus (AcMNPV) has been
widely used as a bioinsecticide and a protein expression vector. Despite their importance …

Pompe disease (glycogen storage disease type II) is caused by mutations in acid α-
glucosidase (GAA) resulting in lysosomal pathology and impairment of the muscular and …