Estrogen and the cardiovascular system
AA Knowlton, AR Lee - Pharmacology & therapeutics, 2012 - Elsevier
Estrogen is a potent steroid with pleiotropic effects, which have yet to be fully elucidated.
Estrogen has both nuclear and non-nuclear effects. The rapid response to estrogen, which …
Estrogen has both nuclear and non-nuclear effects. The rapid response to estrogen, which …
Estrogen receptors and the metabolic network
RPA Barros, JÅ Gustafsson - Cell metabolism, 2011 - cell.com
The metabolic syndrome has reached pandemic level worldwide, and evidence is that
estradiol plays a key role in its development. The discovery of the second estrogen receptor …
estradiol plays a key role in its development. The discovery of the second estrogen receptor …
[HTML][HTML] Sex, gender, and sex hormones in pulmonary hypertension and right ventricular failure
J Hester, C Ventetuolo, T Lahm - Comprehensive Physiology, 2019 - ncbi.nlm.nih.gov
Pulmonary hypertension (PH) encompasses a syndrome of diseases that are characterized
by elevated pulmonary artery pressure and pulmonary vascular remodeling and that …
by elevated pulmonary artery pressure and pulmonary vascular remodeling and that …
Statement on pregnancy in pulmonary hypertension from the Pulmonary Vascular Research Institute
AR Hemnes, DG Kiely, BA Cockrill… - Pulmonary …, 2015 - journals.sagepub.com
Pregnancy outcomes in patients with pulmonary hypertension remain poor despite
advanced therapies. Although consensus guidelines recommend against pregnancy in …
advanced therapies. Although consensus guidelines recommend against pregnancy in …
Calcium-mediated cell death during myocardial reperfusion
D Garcia-Dorado, M Ruiz-Meana, J Inserte… - Cardiovascular …, 2012 - academic.oup.com
Reperfusion may induce additional cell death in patients with acute myocardial infarction
receiving primary angioplasty or thrombolysis. Altered intracellular Ca2+ handling was …
receiving primary angioplasty or thrombolysis. Altered intracellular Ca2+ handling was …
The effects of oestrogens and their receptors on cardiometabolic health
Cardiovascular disease (CVD) is one of the leading causes of mortality in developed
countries. The incidence of CVD is sexually dimorphic, and research has focused on the …
countries. The incidence of CVD is sexually dimorphic, and research has focused on the …
Progress in solving the sex hormone paradox in pulmonary hypertension
T Lahm, RM Tuder, I Petrache - American Journal of …, 2014 - journals.physiology.org
Pulmonary arterial hypertension (PAH) is a devastating and progressive disease with
marked morbidity and mortality. Even though being female represents one of the most …
marked morbidity and mortality. Even though being female represents one of the most …
17β-Estradiol attenuates hypoxic pulmonary hypertension via estrogen receptor–mediated effects
T Lahm, M Albrecht, AJ Fisher, M Selej… - American journal of …, 2012 - atsjournals.org
Rationale: 17β-Estradiol (E2) attenuates hypoxic pulmonary vasoconstriction and hypoxic
pulmonary hypertension (HPH) through an unknown mechanism that may involve estrogen …
pulmonary hypertension (HPH) through an unknown mechanism that may involve estrogen …
Estradiol improves right ventricular function in rats with severe angioproliferative pulmonary hypertension: effects of endogenous and exogenous sex hormones
AL Frump, KN Goss, A Vayl… - … of Physiology-Lung …, 2015 - journals.physiology.org
Estrogens are disease modifiers in PAH. Even though female patients exhibit better right
ventricular (RV) function than men, estrogen effects on RV function (a major determinant of …
ventricular (RV) function than men, estrogen effects on RV function (a major determinant of …
The Role of 17β-Estradiol and Estrogen Receptors in Regulation of Ca2+ Channels and Mitochondrial Function in Cardiomyocytes
S Mahmoodzadeh, E Dworatzek - Frontiers in Endocrinology, 2019 - frontiersin.org
Numerous epidemiological, clinical, and animal studies showed that cardiac function and
manifestation of cardiovascular diseases (CVDs) are different between males and females …
manifestation of cardiovascular diseases (CVDs) are different between males and females …