Gender differences in apoptotic signaling in heart failure due to volume overload

MR Dent, PS Tappia, NS Dhalla - Apoptosis, 2010 - Springer
This study examined sex differences in the regulation of pro-and anti-apoptotic proteins in
cardiac hypertrophy and heart failure due to volume overload induced by arteriovenous (AV) …

Age-related differences in cardiac ischemia–reperfusion injury: effects of estrogen deficiency

DH Korzick, TS Lancaster - Pflügers Archiv-European Journal of …, 2013 - Springer
Despite conflicting evidence for the efficacy of hormone replacement therapy in
cardioprotection of postmenopausal women, numerous studies have demonstrated …

The role of estrogens and vitamin D in cardiomyocyte protection: a female perspective

C Crescioli - Biomolecules, 2021 - mdpi.com
Women experience a dramatical raise in cardiovascular events after menopause. The
decline in estrogens is pointed to as the major responsible trigger for the increased risk of …

Oestrogen receptor β activation protects against myocardial infarction via notch1 signalling

M Du, J Shan, A Feng, S Schmull, J Gu… - Cardiovascular Drugs and …, 2020 - Springer
Purpose Oestrogen receptor β is believed to exert a cardioprotective effect against
ischaemic injury. Nonetheless, the mechanism underlying its protective action remains to be …

Targeted basic research to highlight the role of estrogen and estrogen receptors in the cardiovascular system

E Dworatzek, S Mahmoodzadeh - Pharmacological research, 2017 - Elsevier
Epidemiological, clinical and animal studies revealed that sex differences exist in the
manifestation and outcome of cardiovascular disease (CVD). The underlying molecular …

Estrogen Receptors Are Involved in the Neuroprotective Effect of Silibinin in Aβ1–42-Treated Rats

X Song, B Liu, L Cui, B Zhou, L Liu, W Liu, G Yao… - Neurochemical …, 2018 - Springer
Alzheimer's disease (AD) is a progressive neurodegenerative disease that is characterized
by a cascade of pathologic changes. A widely discussed theory indicates that amyloid β (Aβ) …

Sex differences in animal models for cardiovascular diseases and the role of estrogen

S Mahmoodzadeh, D Fliegner, E Dworatzek - Sex and Gender Differences …, 2012 - Springer
Clinical findings show sex differences in the manifestation of a number of cardiovascular
diseases (CVD). However, the underlying molecular mechanisms are incompletely …

Transcriptomic effects on the mouse heart following 30 days on the international space station

AL Veliz, L Mamoun, L Hughes, R Vega, B Holmes… - Biomolecules, 2023 - mdpi.com
Efforts to understand the impact of spaceflight on the human body stem from growing interest
in long-term space travel. Multiple organ systems are affected by microgravity and radiation …

Pharmacology of doping agents—mechanisms promoting muscle hypertrophy

MK Parr, A Müller-Schöll - AIMS Molecular Science, 2018 - refubium.fu-berlin.de
Doping with performance enhancing substances in professional andamateur sports has
increasingly gained awareness. Furthermore, not only thenumber but also the variety of …

Adjuvant radiotherapy-induced cardiac changes among patients with early breast cancer: a three-year follow-up study

T Skyttä, S Tuohinen, T Luukkaala, V Virtanen… - Acta …, 2019 - Taylor & Francis
Background: In this study, we evaluate the evolution of cardiac changes during a three-year
follow-up after adjuvant breast radiotherapy (RT). Methods: Sixty patients with left-sided and …