Er-xian ameliorates myocardial ischemia-reperfusion injury in rats through RISK pathway involving estrogen receptors
M Qiang, HAO Jiping, LIU Huihui, YIN Jia… - Chinese journal of …, 2022 - Elsevier
Curculigo orchioides (CUR) and Epimedium (EPI) are traditional Chinese medicines with
estrogen-like biological activity, called Xianmao and Xianlingpi (Er-xian) in Chinese …
estrogen-like biological activity, called Xianmao and Xianlingpi (Er-xian) in Chinese …
Role of Akt-dependent pathway in resveratrol-mediated cardioprotection after trauma-hemorrhage
YF Tsai, FC Liu, YT Lau, HP Yu - Journal of Surgical Research, 2012 - Elsevier
BACKGROUND: Resveratrol has been shown to have protective effects for patients in shock-
like states, and Akt (protein kinase B) is known to play a role in pro-inflammatory events in …
like states, and Akt (protein kinase B) is known to play a role in pro-inflammatory events in …
Tid1‐S attenuates LPS‐induced cardiac hypertrophy and apoptosis through ER‐a mediated modulation of p‐PI3K/p‐Akt signaling cascade
Myocardial dysfunction is clinically relevant? repercussion that follows sepsis. Tid 1 protein
has been implicated in many biological process. However, the role of Tid 1 in …
has been implicated in many biological process. However, the role of Tid 1 in …
Estrogen-induced SDF-1 production is mediated by estrogen receptor-α in female hearts after acute ischemia and reperfusion
C Huang, H Gu, Y Wang, M Wang - Surgery, 2011 - Elsevier
BACKGROUND: Gender differences exist in myocardial response to acute
ischemia/reperfusion (I/R) injury and estrogen mediates cardioprotection in the female heart …
ischemia/reperfusion (I/R) injury and estrogen mediates cardioprotection in the female heart …
The actual role of receptors as cancer markers, biochemical and clinical aspects: receptors in breast cancer
M Brennan, B Lim - Advances in Cancer Biomarkers: From biochemistry to …, 2015 - Springer
A biomarker is a characteristic that is objectively measured and evaluated as an indicator of
normal biological processes, pathogenic processes, or pharmacologic responses to a …
normal biological processes, pathogenic processes, or pharmacologic responses to a …
Sex and gender differences in cardiovascular disease
L Groban, SH Lindsey, H Wang, AK Alencar - Sex differences in physiology, 2016 - Elsevier
Cardiovascular disease (CVD) is the leading cause of death and disability in Western
societies. The epidemiology, presentation, pathophysiology, and outcomes of CVD and its …
societies. The epidemiology, presentation, pathophysiology, and outcomes of CVD and its …
The prognostic impact of Akt isoforms, PI3K and PTEN related to female steroid hormone receptors in soft tissue sarcomas
A Valkov, TK Kilvaer, SW Sorbye, T Donnem… - Journal of Translational …, 2011 - Springer
Abstract Background The PI3K/Akt pathway is involved in cellular survival pathways by
inhibiting apoptotic processes and stimulating cell growth and proliferation. Its negative …
inhibiting apoptotic processes and stimulating cell growth and proliferation. Its negative …
Estrogen receptor beta does not influence ischemic tolerance in the aged female rat heart
NJ Tomicek, JL Miller‐Lee, JC Hunter… - Cardiovascular …, 2013 - Wiley Online Library
Introduction: Ischemic heart disease remains the leading cause of morbidity and mortality in
aged women, with a 2‐to 3‐fold increase in incidence following menopause. Clinical trials …
aged women, with a 2‐to 3‐fold increase in incidence following menopause. Clinical trials …
Treatment with 17β‐estradiol protects donor heart against brain death effects in female rat
R Armstrong‐Jr, FY Ricardo‐da‐Silva… - Transplant …, 2020 - Wiley Online Library
The viability of donor organs is reduced by hemodynamic and immunologic alterations
caused by brain death (BD). Female rats show higher heart inflammation associated with the …
caused by brain death (BD). Female rats show higher heart inflammation associated with the …
Diabetes mellitus associated cardiovascular signalling alteration: a need for the revisit
AK Sharma, D Khanna - Cellular signalling, 2013 - Elsevier
Diabetes mellitus, a chronic metabolic disorder, is recognized as a root cause of
cardiovascular disorders. A long-term and uncontrolled diabetes mellitus coincides with the …
cardiovascular disorders. A long-term and uncontrolled diabetes mellitus coincides with the …