Curculigo orchioides (CUR) and Epimedium (EPI) are traditional Chinese medicines with
estrogen-like biological activity, called Xianmao and Xianlingpi (Er-xian) in Chinese …

BACKGROUND: Resveratrol has been shown to have protective effects for patients in shock-
like states, and Akt (protein kinase B) is known to play a role in pro-inflammatory events in …

Myocardial dysfunction is clinically relevant? repercussion that follows sepsis. Tid 1 protein
has been implicated in many biological process. However, the role of Tid 1 in …

BACKGROUND: Gender differences exist in myocardial response to acute
ischemia/reperfusion (I/R) injury and estrogen mediates cardioprotection in the female heart …

A biomarker is a characteristic that is objectively measured and evaluated as an indicator of
normal biological processes, pathogenic processes, or pharmacologic responses to a …

Cardiovascular disease (CVD) is the leading cause of death and disability in Western
societies. The epidemiology, presentation, pathophysiology, and outcomes of CVD and its …

Abstract Background The PI3K/Akt pathway is involved in cellular survival pathways by
inhibiting apoptotic processes and stimulating cell growth and proliferation. Its negative …

Introduction: Ischemic heart disease remains the leading cause of morbidity and mortality in
aged women, with a 2‐to 3‐fold increase in incidence following menopause. Clinical trials …

The viability of donor organs is reduced by hemodynamic and immunologic alterations
caused by brain death (BD). Female rats show higher heart inflammation associated with the …

Diabetes mellitus, a chronic metabolic disorder, is recognized as a root cause of
cardiovascular disorders. A long-term and uncontrolled diabetes mellitus coincides with the …