A comparative overview of epigenomic profiling methods

M Mehrmohamadi, MH Sepehri, N Nazer… - Frontiers in cell and …, 2021 - frontiersin.org
In the past decade, assays that profile different aspects of the epigenome have grown
exponentially in number and variation. However, standard guidelines for researchers to …

Materials control of the epigenetics underlying cell plasticity

S Nemec, KA Kilian - Nature Reviews Materials, 2021 - nature.com
The dynamic epigenetic landscape directs gene expression patterns that dictate cellular
form and function, and drive the assembly of cells into tissues. The high degree of plasticity …

Understanding epigenetic effects of endocrine disrupting chemicals: from mechanisms to novel test methods

A Alavian‐Ghavanini, J Rüegg - Basic & clinical pharmacology …, 2018 - Wiley Online Library
Endocrine‐disrupting chemicals (EDC s) are man‐made chemicals that interfere with
hormonal signalling pathways. They are used in, for example, production of common …

DNA methylation in inflammatory genes among children with obstructive sleep apnea

J Kim, R Bhattacharjee, A Khalyfa… - American journal of …, 2012 - atsjournals.org
Background: Pediatric obstructive sleep apnea (OSA) leads to multiple end-organ
morbidities that are mediated by the cumulative burden of oxidative stress and inflammation …

Epigenetic mechanisms in gastric cancer

CO Gigek, ES Chen, DQ Calcagno, F Wisnieski… - …, 2012 - Taylor & Francis
Cancer is considered one of the major health issues worldwide, and gastric cancer
accounted for 8% of total cases and 10% of total deaths in 2008. Gastric cancer is …

A new synthetic histone deacetylase inhibitor, MHY2256, induces apoptosis and autophagy cell death in endometrial cancer cells via p53 acetylation

U De, JY Son, R Sachan, YJ Park, D Kang… - International Journal of …, 2018 - mdpi.com
We previously discovered a novel sirtuin (SIRT) inhibitor, MHY2256, that exerts anticancer
activity through p53 acetylation in MCF-7 human breast cancer cells. We investigated the …

The marbled crayfish: a new model organism for research on development, epigenetics and evolutionary biology

G Vogt - Journal of Zoology, 2008 - Wiley Online Library
Abstract Model organisms have contributed significantly to the understanding of basic
biological phenomena. Suitable animal models are at hand for some research disciplines …

[HTML][HTML] Sex differences in neurodevelopmental abnormalities caused by early-life anaesthesia exposure: a narrative review

OH Cabrera, T Gulvezan, B Symmes… - British journal of …, 2020 - Elsevier
Exposure to anaesthetic drugs during the fetal or neonatal period induces widespread
neuronal apoptosis in the brains of rodents and non-human primates. Hundreds of …

Rapid evolution of insects to global environmental change: conceptual issues and empirical gaps

JR Garnas - Current opinion in insect science, 2018 - Elsevier
Understanding how insects will respond both ecologically and evolutionarily to complex and
interacting factors linked to global change is an important challenge that underpins our …

Embryonic Developmental Temperatures Modulate Thermal Acclimation of Performance Curves in Tadpoles of the Frog Limnodynastes peronii

F Seebacher, VS Grigaltchik - PLoS One, 2014 - journals.plos.org
Performance curves of physiological rates are not fixed, and determining the extent to which
thermal performance curves can change in response to environmental signals is essential to …