Colorectal cancer (CRC), a leading cause of cancer-related death worldwide, evolves as a
result of the stepwise accumulation of a series of genetic and epigenetic alterations in the …

Colorectal cancer is a leading cause of cancer related deaths worldwide. One of the
hallmarks of cancer and a fundamental trait of virtually all gastrointestinal cancers is …

N6-methyladenosine (m 6 A) is the most pervasive RNA modification and is recognized as a
novel epigenetic regulation in RNA metabolism. Although the m 6 A modification involves …

Resistance to oxaliplatin is a major obstacle hindering the clinical treatment of colorectal
cancer, but the underlying immunological mechanism has not yet been well illustrated. As a …

Simple Summary Immune Checkpoint Inhibitors (ICIs) have demonstrated clinical efficacy in
Microsatellite Instability High Colorectal Cancer (MSI-H CRC). However, in Microsatellite …

Colorectal cancer (CRC) is considered as the second most common cancer worldwide. For
the past few years, the role of immunotherapy has been extensively studied and it has been …

Colorectal cancer (CRC) is one of the most common malignancies and is a major cause of
cancer-related deaths worldwide. Thus, there is a clinical need to improve early detection of …

Simple Summary The mortality of colorectal cancer is principally related to metastatic
disease at the time of diagnosis or to the growth of initially undetectable micro-metastasis …

The synthesis, characterization, and in vitro activity of a cyclohexane-1 R, 2 R-diamine-
based Pt (IV) derivative containing the histone deacetylase inhibitor rac-2-(2-propynyl) …

Background Yogurt is a commonly consumed fermented food. Regular yogurt consumption
may contribute to a favorable gut microbiome and gut health, but few epidemiologic studies …