Major depressive disorder is one of the most disabling mental disorders worldwide.
Increasing preclinical and clinical studies have highlighted that compositional and functional …

The intestinal epithelial barrier (IEB) is one of the largest interfaces between the
environment and the internal milieu of the body. It is essential to limit the passage of harmful …

A large body of evidence has emerged in the past decade supporting a role for the gut
microbiome in the regulation of blood pressure. The field has moved from association to …

Systemic inflammation has been suggested to have a pivotal role in atherothrombosis, but
the factors that trigger systemic inflammation have not been fully elucidated …

Changes in the composition of gut-associated microbial communities are associated with
many human illnesses, but the factors driving dysbiosis remain incompletely understood …

The intestinal mucosal barrier, also referred to as intestinal barrier, is widely recognized as a
critical player in gut homeostasis maintenance as it ensures the complex crosstalk between …

Background Ulcerative colitis (UC) is an inflammatory bowel disease (IBD) characterized by
diffuse inflammation of the colonic mucosa and a relapsing and remitting course. The current …

The prevalence of inflammatory bowel disease (IBD), which includes ulcerative colitis (UC)
and Crohn's disease (CD), increases gradually worldwide in the past decades. IBD is …

Background Disease resistance phenotypes are associated with immune regulatory
functions and immune tolerance and have implications for both the livestock industry and …

Short-chain fatty acids (SCFAs) are metabolites generated by bacterial fermentation of
dietary fiber (DF) in the hindgut. SCFAs are mainly composed of acetate, propionate and …