FUNDC1-mediated mitophagy triggered by mitochondrial ROS is partially involved in 1-nitropyrene-evoked placental progesterone synthesis inhibition and …

J Li, X Dong, JY Liu, L Gao, WW Zhang… - Science of The Total …, 2024 - Elsevier
Intrauterine growth retardation (IUGR) is a major cause of perinatal morbidity and mortality.
Previous studies showed that 1-nitropyrene (1-NP), an atmospheric pollutant, induces …

[HTML][HTML] Nrf2/PINK1-mediated mitophagy induction alleviates sodium fluoride-induced hepatic injury by improving mitochondrial function, oxidative stress, and …

C Song, A Zhang, M Zhang, Y Song, H Huangfu… - Ecotoxicology and …, 2023 - Elsevier
Mitophagy has distinct functions, which can lead to either protection or damage of tissues.
Though current evidence indicated that NaF triggers mitophagy, the role and regulation of …

Cadmium‐induced pyroptosis is mediated by PERK/TXNIP/NLRP3 signaling in SH‐SY5Y cells

Z Li, Y Shi, Y Wang, H Qi, H Chen… - Environmental …, 2023 - Wiley Online Library
Cadmium (Cd) is a hypertoxic heavy metal that may be exposed to environmental pollutants
by humans and animals. It can lead to cognitive disfunction, and is linked to …

Combined effects of cadmium and lead on growth performance and kidney function in broiler chicken

M Zhao, L Xie, W Huang, M Li, X Gu, W Zhang… - … Trace Element Research, 2024 - Springer
Abstract Cadmium (Cd) and lead (Pb) are heavy metals prevalent in the environment and
feed, and they reduce production performance of domestic animals, as well as they result in …

Environmental cadmium inhibits testicular testosterone synthesis via Parkin-dependent MFN1 degradation

TT Wang, HL Zhu, KW Ouyang, H Wang, YX Luo… - Journal of Hazardous …, 2024 - Elsevier
Low testosterone (T) levels are associated with many common diseases, such as obesity,
male infertility, depression, and cardiovascular disease. It is well known that environmental …

Maternal prednisone exposure during pregnancy elevates susceptibility to osteoporosis in female offspring: The role of mitophagy/FNDC5 alteration in skeletal muscle

ZY Du, HL Zhu, W Chang, YF Zhang, Q Ling… - Journal of Hazardous …, 2024 - Elsevier
Maternal exposure to glucocorticoids has been associated with adverse outcomes in
offspring. However, the consequences and mechanisms of gestational exposure to …

[HTML][HTML] miR-6769b-5p targets CCND-1 to regulate proliferation in cadmium-treated placental trophoblasts: association with the impairment of fetal growth

YW Xiong, YJ Feng, T Wei, X Zhang, LL Tan… - Ecotoxicology and …, 2022 - Elsevier
Environmental cadmium (Cd) is positively associated with placental impairment and fetal
growth retardation. Nevertheless, its potential mechanisms remain unclear. microRNAs …

Association of co-exposure to metal (loid) s during pregnancy with birth outcomes in the Tibetan plateau

L Zhao, T Li, H Wang, YM Fan, Y Xiao, X Wang… - Chemosphere, 2023 - Elsevier
Maternal metal (loid) s exposure has been related to birth outcomes but the results are still
inconclusive. Most previous studies have discussed the single metal (loid) s, neglecting the …

[HTML][HTML] Molecular crosstalk and putative mechanisms underlying mitochondrial quality control: The hidden link with methylmercury-induced cognitive impairment

Y Hu, L Zhang, C Tian, F Chen, P Li, A Zhang… - Ecotoxicology and …, 2024 - Elsevier
Methylmercury (MeHg) is a neurotoxin associated with foetal neurodevelopmental and adult
cognitive deficits. Neurons are highly dependent on the tricarboxylic acid cycle and oxidative …

Mechanism of histone deacetylase HDAC2 in FOXO3-mediated trophoblast pyroptosis in preeclampsia

J Liu, W Yang - Functional & Integrative Genomics, 2023 - Springer
Abstract Histone deacetylase 2 (HDAC2) has been demonstrated to regulate trophoblast
behaviors. However, its role in trophoblast pyroptosis remains unknown. This study sought …