A growing preclinical and clinical body of work on the effects of chronic drug use and drug
addiction has extended the scope of inquiry from the putative reward-related subcortical …

Retention in medication-assisted treatment among opiate-dependent patients is associated
with better outcomes. This systematic review (55 articles, 2010–2014) found wide variability …

The Hierarchical Taxonomy of Psychopathology (HiTOP) is an empirical effort to address
limitations of traditional mental disorder diagnoses. These include arbitrary boundaries …

The loss of control over drug intake that occurs in addiction was initially believed to result
from disruption of subcortical reward circuits. However, imaging studies in addictive …

Cognitive contributions to the behaviors observed in substance and non-substance
addictions have been investigated and characterized. Based on models of drug addictions …

With the increasing push to legalize cannabis in Western nations, there is a need to gage
the potential impact of this policy change on vulnerable populations, such as those with …

Economic choice behavior entails the computation and comparison of subjective values. A
central contribution of neuroeconomics has been to show that subjective values are …

Summary Since 1997 the US National Institute on Drug Abuse has advocated a brain
disease model of addiction (BDMA). We assess the strength of evidence for the BDMA in …

Adolescence is a developmental period characterized by suboptimal decisions and actions
that give rise to an increased incidence of unintentional injuries and violence, alcohol and …

Adolescence is a developmental period often characterized as a time of impulsive and risky
choices leading to increased incidence of unintentional injuries and violence, alcohol and …