[HTML][HTML] Molecular mechanisms targeting drug-resistance and metastasis in colorectal cancer: Updates and beyond

S Al Bitar, M El-Sabban, S Doughan… - World Journal of …, 2023 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is the third most diagnosed malignancy and a major leading cause
of cancer-related deaths worldwide. Despite advances in therapeutic regimens, the number …

[HTML][HTML] Anticancer effect of terpenes: focus on malignant melanoma

P Wróblewska-Łuczka, J Cabaj, J Bargieł… - Pharmacological …, 2023 - Springer
Melanoma is a highly aggressive and life-threatening form of skin cancer that accounts for a
significant proportion of cancer-related deaths worldwide. Although conventional cancer …

[HTML][HTML] Characterization of thymoquinone-sulfobutylether-β-cyclodextrin inclusion complex for anticancer applications

EEM Eid, AA Almaiman, SA Alshehade, W Alsalemi… - Molecules, 2023 - mdpi.com
Thymoquinone (TQ) is a quinone derived from the black seed Nigella sativa and has been
extensively studied in pharmaceutical and nutraceutical research due to its therapeutic …

[HTML][HTML] The role of thymoquinone in inflammatory response in chronic diseases

Y Liu, L Huang, MY Kim, JY Cho - International Journal of Molecular …, 2022 - mdpi.com
Anti-inflammatory therapies have been shown to be effective in the prevention of various
cardiovascular diseases, tumors, and cancer complications. Thymoquinone (TQ), the main …

[HTML][HTML] Thymoquinone-loaded lipid nanocapsules with promising anticancer activity for colorectal cancer

M Selmi, A Salek, M Barboura, L Njim, A Trabelsi… - Nanoscale …, 2023 - pubs.rsc.org
Colorectal cancer (CRC) is the third most common worldwide. Depending on its stage,
chemotherapy is usually given after surgery when CRC has already metastasized to other …

[HTML][HTML] Potential anticancer properties and mechanisms of thymoquinone in colorectal cancer

F Sheikhnia, V Rashidi, H Maghsoudi… - Cancer cell …, 2023 - Springer
Colorectal neoplasms are one of the deadliest diseases among all cancers worldwide.
Thymoquinone (TQ) is a natural compound of Nigella sativa that has been used in traditional …

Inclusion of nitrofurantoin into the realm of cancer chemotherapy via biology-oriented synthesis and drug repurposing

PA Elzahhar, HA Nematalla, H Al-Koussa… - Journal of Medicinal …, 2023 - ACS Publications
Structural modifications of the antibacterial drug nitrofurantoin were envisioned, employing
drug repurposing and biology-oriented drug synthesis, to serve as possible anticancer …

[HTML][HTML] The Anticancer Activities of Natural Terpenoids That Inhibit Both Melanoma and Non-Melanoma Skin Cancers

YE Yoon, YJ Jung, SJ Lee - International Journal of Molecular Sciences, 2024 - mdpi.com
The prevalence of two major types of skin cancer, melanoma and non-melanoma skin
cancer, has been increasing worldwide. Skin cancer incidence is estimated to rise …

[HTML][HTML] Innovative Strategies to Combat 5-Fluorouracil Resistance in Colorectal Cancer: The Role of Phytochemicals and Extracellular Vesicles

M Barathan, AK Zulpa, SL Ng, Y Lokanathan… - International Journal of …, 2024 - mdpi.com
Colorectal cancer (CRC) is a significant public health challenge, with 5-fluorouracil (5-FU)
resistance being a major obstacle to effective treatment. Despite advancements, resistance …

Natural Guardians: Natural Compounds as Radioprotectors in Cancer Therapy

A Stasiłowicz-Krzemień, A Gościniak… - International Journal of …, 2024 - mdpi.com
Cancer remains a significant global health challenge, with millions of deaths attributed to it
annually. Radiotherapy, a cornerstone in cancer treatment, aims to destroy cancer cells …