The cannabis derivative marijuana is the most widely used recreational drug in the Western
world and is consumed by an estimated 83 million individuals (∼ 3% of the world …

Abstract N-acylethanolamines (NAEs), including N-palmitoylethanolamine (PEA), N-
oleoylethanolamine (OEA), N-arachidonoylethanolamine (AEA, anandamide), N …

Concerns over reports of suicidal ideation associated with semaglutide treatment, a
glucagon-like peptide 1 receptor (GLP1R) agonist medication for type 2 diabetes (T2DM) …

In the past three decades, total fat and saturated fat intake as a percentage of total calories
has continuously decreased in Western diets, while the intake of omega-6 fatty acid …

Dysregulation of the endogenous lipid mediators endocannabinoids and their G-protein-
coupled cannabinoid receptors 1 and 2 (CB1R and CB2R) has been implicated in a variety …

Fruits and vegetables are important components of a healthy diet. They are rich sources of
vitamins and minerals, dietary fibre and a host of beneficial non-nutrient substances …

Apart from having been used and misused for at least four millennia for, among others,
recreational and medicinal purposes, the cannabis plant and its most peculiar chemical …

Stress affects a constellation of physiological systems in the body and evokes a rapid shift in
many neurobehavioral processes. A growing body of work indicates that the …

Recent insights into the pathophysiologic underlying mechanisms of obesity have led to the
discovery of several promising drug targets and novel therapeutic strategies to address the …

Obesity is a serious and growing worldwide health challenge. Healthy lifestyle choices are
the foundation of obesity treatment. However, weight loss can lead to physiological …