[HTML][HTML] Functions of cationic host defense peptides in immunity

M Hemshekhar, V Anaparti, N Mookherjee - Pharmaceuticals, 2016 - mdpi.com
Cationic host defense peptides are a widely distributed family of immunomodulatory
molecules with antimicrobial properties. The biological functions of these peptides include …

Antimicrobial peptides as novel anti-tuberculosis therapeutics

JP Silva, R Appelberg, FM Gama - Biotechnology advances, 2016 - Elsevier
Tuberculosis (TB), a disease caused by the human pathogen Mycobacterium tuberculosis,
has recently joined HIV/AIDS as the world's deadliest infectious disease, affecting around …

Delivery of LLKKK18 loaded into self-assembling hyaluronic acid nanogel for tuberculosis treatment

JP Silva, C Gonçalves, C Costa, J Sousa… - Journal of Controlled …, 2016 - Elsevier
Tuberculosis (TB), a disease caused by the human pathogen Mycobacterium tuberculosis,
recently joined HIV/AIDS on the top rank of deadliest infectious diseases. Low patient …

Antimicrobial peptides as an alternative to anti-tuberculosis drugs

M AlMatar, EA Makky, G Yakıcı, I Var, B Kayar… - Pharmacological …, 2018 - Elsevier
Tuberculosis (TB) presently accounts for high global mortality and morbidity rates, despite
the introduction four decades ago of the affordable and efficient four-drugs (isoniazid …

Improved burn wound healing by the antimicrobial peptide LLKKK18 released from conjugates with dextrin embedded in a carbopol gel

JP Silva, S Dhall, M Garcia, A Chan, C Costa, M Gama… - Acta biomaterialia, 2015 - Elsevier
Antimicrobial peptides (AMPs) are good candidates to treat burn wounds, a major cause of
morbidity, impaired life quality and resources consumption in developed countries. We took …

[HTML][HTML] Interaction between antimicrobial peptides and mycobacteria

T Gutsmann - Biochimica et Biophysica Acta (BBA)-Biomembranes, 2016 - Elsevier
Mycobacteria can cause different severe health problems, including tuberculosis (TB). The
treatment of TB with conventional antibiotics is successful, however, the number of multi …

[HTML][HTML] Interrelation of adipose tissue macrophages and fibrosis in obesity

N Dahdah, C Tercero-Alcázar, MM Malagón… - Biochemical …, 2024 - Elsevier
Obesity is characterized by adipose tissue expansion, extracellular matrix remodelling and
unresolved inflammation that contribute to insulin resistance and fibrosis. Adipose tissue …

[HTML][HTML] New insights into fibrosis from the ECM degradation perspective: the macrophage-MMP-ECM interaction

X Zhao, J Chen, H Sun, Y Zhang, D Zou - Cell & bioscience, 2022 - Springer
Fibrosis is a pathological feature of a variety of chronic inflammatory diseases that can affect
almost all organs, which can cause severe consequences and even lead to death. Fibrosis …

[HTML][HTML] Short, Synthetic Cationic Peptides Have Antibacterial Activity against Mycobacterium smegmatis by Forming Pores in Membrane and Synergizing with …

K Gupta, S Singh, ML Van Hoek - Antibiotics, 2015 - mdpi.com
Multicellular organisms are constantly exposed to a multitude of pathogenic microbes.
Infection is inhibited in vivo by the innate and adaptive immune system. Mycobacterium …

Cathelicidin‐related antimicrobial peptide alleviates alcoholic liver disease through inhibiting inflammasome activation

F Li, C Zhao, T Shao, Y Liu, Z Gu, M Jiang… - The Journal of …, 2020 - Wiley Online Library
Alcoholic liver disease (ALD) is associated with gut dysbiosis and hepatic inflammasome
activation. While it is known that antimicrobial peptides (AMPs) play a critical role in the …