[HTML][HTML] Biofilm antimicrobial susceptibility through an experimental evolutionary lens

T Coenye, M Bové, T Bjarnsholt - NPJ biofilms and microbiomes, 2022 - nature.com
Experimental evolution experiments in which bacterial populations are repeatedly exposed
to an antimicrobial treatment, and examination of the genotype and phenotype of the …

[HTML][HTML] Prioritization of Critical Factors for Surveillance of the Dissemination of Antibiotic Resistance in Pseudomonas aeruginosa: A Systematic Review

JH Lee, NH Kim, KM Jang, H Jin, K Shin… - International Journal of …, 2023 - mdpi.com
Pseudomonas aeruginosa is the primary opportunistic human pathogen responsible for a
range of acute and chronic infections; it poses a significant threat to immunocompromised …

Experimental evolution of Pseudomonas aeruginosa to colistin in spatially confined microdroplets identifies evolutionary trajectories consistent with adaptation in …

S Disney-McKeethen, S Seo, H Mehta, K Ghosh… - Mbio, 2023 - Am Soc Microbiol
Antibiotic resistance is a continuing global health crisis. Identifying the evolutionary
trajectories leading to increased antimicrobial resistance can be critical to the discovery of …

Co-occurring microflora and mucin drive Pseudomonas aeruginosa diversification and pathoadaptation

MJ Bottery, HK Johansen, JW Pitchford… - ISME …, 2024 - academic.oup.com
While several environmental factors contribute to the evolutionary diversification of the
pathogenic bacterium Pseudomonas aeruginosa during cystic fibrosis lung infections …

The role of hypermutation and collateral sensitivity in antimicrobial resistance diversity of Pseudomonas aeruginosa populations in cystic fibrosis lung infection

J Vanderwoude, S Azimi, TD Read, SP Diggle - Mbio, 2024 - Am Soc Microbiol
Pseudomonas aeruginosa is an opportunistic pathogen which causes chronic, drug-
resistant lung infections in cystic fibrosis (CF) patients. In this study, we explore the role of …

On the de novo emergence of ecological interactions during evolutionary diversification: A conceptual framework and experimental test

NSB Houpt, R Kassen - The American Naturalist, 2023 - journals.uchicago.edu
Ecological interactions are crucial to the structure and function of biological communities, but
we lack a causal understanding of the forces shaping their emergence during evolutionary …

Unraveling Genomic Diversity in Pseudomonas aeruginosa Cystic Fibrosis Lung Infection and Its Impact on Antimicrobial Resistance.

J Vanderwoude, S Azimi, TD Read… - Biorxiv: the Preprint …, 2023 - europepmc.org
Pseudomonas aeruginosa is the predominant bacterial pathogen in the cystic fibrosis (CF)
lung, establishing a chronic, drug-resistant infection often via a single adapting and …

Phage-mediated resolution of genetic conflict alters the evolutionary trajectory of Pseudomonas aeruginosa lysogens

LC Suttenfield, Z Rapti, JH Chandrashekhar… - bioRxiv, 2023 - biorxiv.org
The opportunistic human pathogen Pseudomonas aeruginosa is naturally infected by a
large class of temperate, transposable, Mu-like phages. We examined the genotypic and …

Highlight: Virtual Issue on Host–Pathogen Interactions and Antimicrobial Drug Resistance

C McGrath - 2022 - academic.oup.com
A 2022 Virtual Issue from Genome Biology and Evolution (GBE) highlights recent articles on
the evolutionary dynamics of host–pathogen interactions and antimicrobial drug resistance …

Bacterial community structure and mucin drive Pseudomonas aeruginosa diversification and pathoadaptation

HK Johansen, J Pitchford, VP Friman, M Bottery - 2023 - researchsquare.com
While several environmental factors contribute to the evolutionary diversification of the
pathogenic bacterium Pseudomonas aeruginosa during cystic fibrosis lung infections …