Exosomes play a role as mediators of cell-to-cell communication, thus exhibiting pleiotropic
activities to homeostasis regulation. Exosomal non-coding RNAs (ncRNAs), mainly …

From a clinical, morphological and molecular perspective, prostate cancer is a
heterogeneous disease. Primary prostate cancers are often multifocal, having …

Prostate Cancer Incidence and Survival, by Stage and Race/Ethnicity — United States, 2001–2017
| MMWR Skip directly to site content Skip directly to page options Skip directly to AZ link …

Despite the high long-term survival in localized prostate cancer, metastatic prostate cancer
remains largely incurable even after intensive multimodal therapy. The lethality of advanced …

Chlorogenic acid (CA), also known as 5-O-caffeoylquinic acid, is a dietary phenolic acid
produced by various plant species. CA, is the most ubiquitous compound among the …

Abstract Purpose of Review Neuroendocrine prostate cancer (NEPC) is an aggressive
histologic subtype of prostate cancer that most commonly arises in later stages of prostate …

Cancer has an impressive ability to evolve multiple processes to evade therapies. While
immunotherapies and vaccines have shown great promise, particularly in certain solid …

Background Cancer mortality rates, though not absolute numbers of deaths, have been
decreasing over the last three decades in Europe. Materials and methods We estimated …

We report herein the discovery of highly potent PROTAC degraders of androgen receptor
(AR), as exemplified by compound 34 (ARD-69). ARD-69 induces degradation of AR protein …

Studying prostate cancer is important due to its high annual incidences and mortality rates in
the world. Although prostate cancer mortality rates are reduced using new therapy …