The role of astrocytes in oxidative stress of central nervous system: A mixed blessing

Y Chen, C Qin, J Huang, X Tang, C Liu… - Cell …, 2020 - Wiley Online Library
Central nervous system (CNS) maintains a high level of metabolism, which leads to the
generation of large amounts of free radicals, and it is also one of the most vulnerable organs …

Crosstalk between the oxidative stress and glia cells after stroke: from mechanism to therapies

G Zhu, X Wang, L Chen, C Lenahan, Z Fu… - Frontiers in …, 2022 - frontiersin.org
Stroke is the second leading cause of global death and is characterized by high rates of
mortality and disability. Oxidative stress is accompanied by other pathological processes …

Oxidative Stress‐Mediated Blood‐Brain Barrier (BBB) Disruption in Neurological Diseases

K Song, Y Li, H Zhang, N An, Y Wei… - Oxidative medicine …, 2020 - Wiley Online Library
The blood‐brain barrier (BBB), as a crucial gate of brain‐blood molecular exchange, is
involved in the pathogenesis of multiple neurological diseases. Oxidative stress is caused …

Blood-brain barrier dysfunction in CNS disorders and putative therapeutic targets: an overview

SR Archie, A Al Shoyaib, L Cucullo - Pharmaceutics, 2021 - mdpi.com
The blood-brain barrier (BBB) is a fundamental component of the central nervous system
(CNS). Its functional and structural integrity is vital to maintain the homeostasis of the brain …

Gliotoxicity and glioprotection: the dual role of glial cells

A Quincozes-Santos, CL Santos… - Molecular …, 2021 - Springer
Glial cells (astrocytes, oligodendrocytes and microglia) are critical for the central nervous
system (CNS) in both physiological and pathological conditions. With this in mind, several …

[HTML][HTML] Diabetic peripheral neuropathy: pathogenetic mechanisms and treatment

J Zhu, Z Hu, Y Luo, Y Liu, W Luo, X Du… - Frontiers in …, 2024 - frontiersin.org
Diabetic peripheral neuropathy (DPN) refers to the development of peripheral nerve
dysfunction in patients with diabetes when other causes are excluded. Diabetic distal …

Recent advances in FSCV detection of neurochemicals via waveform and carbon microelectrode modification

H Rafi, AG Zestos - Journal of The Electrochemical Society, 2021 - iopscience.iop.org
Fast scan cyclic voltammetry (FSCV) is an analytical technique that was first developed over
30 years ago. Since then, it has been extensively used to detect dopamine using carbon …

Long-term exposure to environmental diclofenac concentrations impairs growth and induces molecular changes in Lymnaea stagnalis freshwater snails

L Bouly, F Courant, E Bonnafé, JL Carayon… - Chemosphere, 2022 - Elsevier
As pharmaceutical substances are highly used in human and veterinary medicine and
subsequently released in the environment, they represent emerging contaminants in the …

Glutathione-Mediated Neuroprotective Effect of Purine Derivatives

N Matsumura, K Aoyama - International Journal of Molecular Sciences, 2023 - mdpi.com
Numerous basic studies have reported on the neuroprotective properties of several purine
derivatives such as caffeine and uric acid (UA). Epidemiological studies have also shown …

Using metabolomics to identify the exposure and functional biomarkers of ginger

D Esquivel-Alvarado, S Zhang, C Hu… - Journal of agricultural …, 2022 - ACS Publications
Liquid chromatography–mass spectrometry (LC–MS)-based metabolomics has become an
important tool to increase our understanding of how diet affects human health. However …