The incidence of esophageal adenocarcinoma (EAC) has increased in many Western
countries and is higher in men than women. Some risk factors for EAC have been identified …

Human gut microbiota play an essential role in both healthy and diseased states of humans.
In the past decade, the interactions between microorganisms and tumors have attracted …

Proton pump inhibitors (PPIs) are common medications within the practice of
gastroenterology. These drugs, which act through the irreversible inhibition of the …

Cancer treatment has been advanced with the advent of immune checkpoint inhibitors (ICIs)
exemplified by anti-cytotoxic T-lymphocyte-associated protein 4 (CTLA-4), anti-programmed …

Surgery involving the gastrointestinal tract continues to prove challenging because of the
persistence of unpredictable complications such as anastomotic leakage and life …

A number of studies have identified that gut microbiota influences the development of
cancer. However, there is little known about gut microbiota and esophageal cancer (EC) …

The incidence of esophageal adenocarcinoma (EAC) has increased in recent decades, and
its 5-year survival rate is less than 20%. As a well-established precursor, patients with …

Purpose Increasing evidence indicates that the microbiome may influence tumor growth and
modulate the tumor microenvironment of gastrointestinal cancers. However, the role of oral …

The esophageal mucosa is among the sites colonized by human microbiota, the complex
microbial ecosystem that colonizes various body surfaces and is increasingly recognized to …

Background & Aims Microbiota composition and mechanisms of host–microbiota
interactions in the esophagus are unclear. We aimed to uncover fundamental information …