Acinetobacter baumannii Biofilm Formation and Its Role in Disease Pathogenesis: A Review

A Gedefie, W Demsis, M Ashagrie, Y Kassa… - Infection and drug …, 2021 - Taylor & Francis
Acinetobacter species, particularly Acinetobacter baumannii, is the first pathogen on the
critical priority list of pathogens for novel antibiotics to become a “red-alert” human …

Biology of Acinetobacter baumannii: Pathogenesis, Antibiotic Resistance Mechanisms, and Prospective Treatment Options

CR Lee, JH Lee, M Park, KS Park, IK Bae… - Frontiers in cellular …, 2017 - frontiersin.org
Acinetobacter baumannii is undoubtedly one of the most successful pathogens responsible
for hospital-acquired nosocomial infections in the modern healthcare system. Due to the …

[HTML][HTML] Impact of COVID-19 pandemic on multidrug resistant gram positive and gram negative pathogens: A systematic review

U Abubakar, M Al-Anazi, J Rodríguez-Baño - Journal of infection and …, 2023 - Elsevier
Background There is paucity of data describing the impact of COVID-19 pandemic on
antimicrobial resistance. This review evaluated the changes in the rate of multidrug resistant …

[HTML][HTML] Antimicrobial resistance in Acinetobacter baumannii: From bench to bedside

MF Lin, CY Lan - World Journal of Clinical Cases: WJCC, 2014 - ncbi.nlm.nih.gov
Acinetobacter baumannii (A. baumannii) is undoubtedly one of the most successful
pathogens in the modern healthcare system. With invasive procedures, antibiotic use and …

Mechanisms of β-lactam antimicrobial resistance and epidemiology of major community-and healthcare-associated multidrug-resistant bacteria

SS Tang, A Apisarnthanarak, LY Hsu - Advanced drug delivery reviews, 2014 - Elsevier
Alexander Fleming's discovery of penicillin heralded an age of antibiotic development and
healthcare advances that are premised on the ability to prevent and treat bacterial infections …

Structural and functional diversity of resistance–nodulation–cell division transporters

PA Klenotic, MA Moseng, CE Morgan, EW Yu - Chemical reviews, 2020 - ACS Publications
Multidrug resistant (MDR) bacteria are a global threat with many common infections
becoming increasingly difficult to eliminate. While significant effort has gone into the …

Phenotypic and genotypic characterization of carbapenem-resistant Acinetobacter baumannii isolates from Egypt

A Abouelfetouh, AS Torky, E Aboulmagd - Antimicrobial Resistance & …, 2019 - Springer
Background Antibiotic use is largely under-regulated in Egypt leading to the emergence of
resistant isolates. Carbapenems are last resort agents to treat Acinetobacter baumannii …

Cryo-electron microscopy structure of an Acinetobacter baumannii multidrug efflux pump

CC Su, CE Morgan, S Kambakam, M Rajavel, H Scott… - MBio, 2019 - Am Soc Microbiol
Resistance-nodulation-cell division multidrug efflux pumps are membrane proteins that
catalyze the export of drugs and toxic compounds out of bacterial cells. Within the …

Cryoelectron microscopy structures of AdeB illuminate mechanisms of simultaneous binding and exporting of substrates

CE Morgan, P Glaza, IV Leus, A Trinh, CC Su, M Cui… - MBio, 2021 - Am Soc Microbiol
Acinetobacter baumannii is a Gram-negative pathogen that has emerged as one of the most
highly antibiotic-resistant bacteria worldwide. Multidrug efflux within these highly drug …

Multidrug-resistant Acinetobacter baumannii in healthcare settings in Africa

N Agyepong, F Fordjour, A Owusu-Ofori - Frontiers in Tropical …, 2023 - frontiersin.org
The emergence of multidrug-resistant Acinetobacter baumannii is a major concern to
healthcare providers and facilities in many parts of the world. This bacterial pathogen is …