Immune tolerance for autoimmune disease and cell transplantation

X Luo, SD Miller, LD Shea - Annual review of biomedical …, 2016 - annualreviews.org
The undesired destruction of healthy cells, either endogenous or transplanted, by the
immune system results in the loss of tissue function or limits strategies to restore tissue …

Using biomaterials to rewire the process of wound repair

A Stejskalová, BD Almquist - Biomaterials science, 2017 - pubs.rsc.org
Wound healing is one of the most complex processes that our bodies must perform. While
our ability to repair wounds is often taken for granted, conditions such as diabetes, obesity …

Polycistronic delivery of IL-10 and NT-3 promotes oligodendrocyte myelination and functional recovery in a mouse spinal cord injury model

DR Smith, CM Dumont, J Park, AJ Ciciriello… - … Engineering Part A, 2020 - liebertpub.com
One million estimated cases of spinal cord injury (SCI) have been reported in the United
States and repairing an injury has constituted a difficult clinical challenge. The complex …

Immunomodulation for tissue repair and regeneration

S Moon, J Hong, S Go, BS Kim - Tissue engineering and regenerative …, 2023 - Springer
Various immune cells participate in repair and regeneration following tissue injury or
damage, orchestrating tissue inflammation and regeneration processes. A deeper …

Biomaterial strategies to bolster neural stem cell-mediated repair of the central nervous system

G Tejeda, AJ Ciciriello, CM Dumont - Cells Tissues Organs, 2023 - karger.com
Stem cell therapies have the potential to not only repair, but to regenerate tissue of the
central nervous system (CNS). Recent studies demonstrate that transplanted stem cells can …

Immunomodulating hydrogels as stealth platform for drug delivery applications

Z Rezaei, D Yilmaz-Aykut, FM Tourk, N Bassous… - Pharmaceutics, 2022 - mdpi.com
Non-targeted persistent immune activation or suppression by different drug delivery
platforms can cause adverse and chronic physiological effects including cancer and arthritis …

Macrophage Mechano-Responsiveness Within Three-Dimensional Tissue Matrix upon Mechanotherapy-Associated Strains

P Babaniamansour, D Jacho, A Teow… - … Engineering Part A, 2024 - liebertpub.com
Mechano-rehabilitation, also known as mechanotherapy, represents the forefront of
noninvasive treatment for musculoskeletal (MSK) tissue disorders, encompassing conditions …

[HTML][HTML] Biomaterial-based delivery systems of nucleic acid for regenerative research and regenerative therapy

J Jo, JQ Gao, Y Tabata - Regenerative therapy, 2019 - Elsevier
Regenerative medicine is a new and promising medical method aiming at treating patients
with defective or dysfunctional tissues by maintaining or enhancing the biological activity of …

Stem cells for the treatment of heart failure

P Menasché, V Vanneaux - Current research in translational medicine, 2016 - Elsevier
Stem cell-based therapy is currently tested in several trials of chronic heart failure. The main
question is to determine how its implementation could be extended to standard clinical …

Fas Ligand-Modified Scaffolds Protect Stem Cell Derived β-Cells by Modulating Immune Cell Numbers and Polarization

F Li, K Crumley, E Bealer, JL King, E Saito… - … Applied Materials & …, 2022 - ACS Publications
Stem cell derived β-cells have demonstrated the potential to control blood glucose levels
and represent a promising treatment for Type 1 diabetes (T1D). Early engraftment post …