Cardiovascular disease is the leading cause of mortality and morbidity throughout the world,
accounting for 16.7 million deaths each year. The underlying pathological process for the …

Atherosclerosis is an immune-mediated chronic inflammatory disease that leads to the
development of fatty plaques in the arterial walls, ultimately increasing the risk of thrombosis …

C-reactive protein is involved in a plethora of pathophysiological conditions. Many genetic
loci associated with C-reactive protein are annotated to lipid and glucose metabolism genes …

The benefits of current state-of-the-art treatments to combat atherosclerotic cardiovascular
disease (ASCVD) have stagnated. Treatments are mostly based on controlling …

The renin-angiotensin system (RAS) is a central modulator of cardiovascular physiology.
Pathophysiology of hypertension is commonly accompanied by hyper-activation of RAS …

Ischemic heart failure (IHF) is a leading cause of morbidity and mortality worldwide, for
which heart transplantation remains the only definitive treatment. IHF manifests from …

In contrast to adult mammals, adult zebrafish can fully regenerate injured cardiac tissue, and
this regeneration process requires an adequate and tightly controlled immune response …

Cardiovascular disease still represents the main cause of mortality worldwide. Despite huge
improvements, atherosclerosis persists as the principal pathological condition, both in stable …

Macrophages are major players in myocardial infarction (MI) and atherosclerosis, two major
cardiovascular diseases (CVD). Atherosclerosis is caused by the buildup of cholesterol‐rich …

Macrophages play an important role in the pathogenesis of atherosclerosis (AS) by
mediating oxidative stress, inflammation and lipid metabolism, which can lead to the …