Highlights•Siderophores are often small molecule natural products.•The defining
characteristic of this compound class is metal chelation.•Siderophores are typically the …

The bacterial endophytes isolated from the halophyte Salicornia brachiata were explored for
the antimicrobial potential to discover novel microbial inhibitors that combat multidrug …

Diabetes mellitus (DM) increases the risk of developing tuberculosis (TB), but the
mechanisms behind diabetes-TB comorbidity are still undefined. Here, we studied the role of …

Infections by drug-resistant bacteria are life-threatening. As iron is a vital element for the
growth of bacteria, iron-chelating agents (siderophores) can be used to arrest their …

Abstract Mycobacterium tuberculosis (M. tuberculosis), the causative agent of tuberculosis
(TB), is responsible for most deaths caused by a bacterium globally. Two main reasons for …

Fast-growing mycobacterial infections have been gradually described in recent years,
mainly because they are associated with a wide range of clinical syndromes, ranging from …

Many bacteria, fungi and graminaceous plants produce organic ligands, termed
siderophores, to scavenge the essential micronutrient iron (Fe). Siderophores are …

Background: The problem of drug-resistant Mycobacterium tuberculosis (M. tb) is alarming
and therefore there is an immediate need for alternative or complementary drugs. This could …

The conventional drug discovery and development process takes a long time and is not
financially viable at times. Repurposing or repositioning existing drugs for treating new …

Introdução: A tuberculose é causada por variantes da espécie Mycobacterium tuberculosis,
acometendo principalmente indivíduos imunocomprometidos. Neste sentido, o bacilo da …