[HTML][HTML] Productive lifecycle of human papillomaviruses that depends upon squamous epithelial differentiation

N Kajitani, A Satsuka, A Kawate, H Sakai - Frontiers in microbiology, 2012 - frontiersin.org
Human papillomaviruses (HPVs) target the stratified epidermis, and can causes diseases
ranging from benign condylomas to malignant tumors. Infections of HPVs in the genital tract …

Transcriptional regulation of the telomerase hTERT gene as a target for cellular and viral oncogenic mechanisms

I Horikawa, JC Barrett - Carcinogenesis, 2003 - academic.oup.com
Malignant transformation from mortal, normal cells to immortal, cancer cells is generally
associated with activation of telomerase and subsequent telomere maintenance. A major …

Life cycle heterogeneity in animal models of human papillomavirus-associated disease

WL Peh, K Middleton, N Christensen, P Nicholls… - Journal of …, 2002 - Am Soc Microbiol
Animal papillomaviruses are widely used as models to study papillomavirus infection in
humans despite differences in genome organization and tissue tropism. Here, we have …

Structure of the intact transactivation domain of the human papillomavirus E2 protein

AA Antson, JE Burns, OV Moroz, DJ Scott, CM Sanders… - Nature, 2000 - nature.com
Papillomaviruses cause warts and proliferative lesions in skin and other epithelia. In a
minority of papillomavirus types ('high risk', including human papillomaviruses 16, 18, 31 …

Functional significance of sequence variation in the E2 gene and the long control region of human papillomavirus type 16.

G Veress, K Szarka, XP Dong… - Journal of General …, 1999 - microbiologyresearch.org
The long control region (LCR) and the E2 protein of human papillomaviruses (HPV) are the
most important viral factors regulating transcription of the viral oncogenes E6 and E7 …

Transcription-independent triggering of the extrinsic pathway of apoptosis by human papillomavirus 18 E2 protein

C Demeret, A Garcia-Carranca, F Thierry - Oncogene, 2003 - nature.com
Cervical carcinomas are most frequently associated with human papillomaviruses (HPV),
whose E6 and E7 oncogenes products induce cellular immortalization. The papillomavirus …

[HTML][HTML] Nucleo-cytoplasmic shuttling of high risk human Papillomavirus E2 proteins induces apoptosis

S Blachon, S Bellanger, C Demeret, F Thierry - Journal of biological …, 2005 - ASBMB
Human Papillomavirus (HPV) E2 proteins are the major viral regulators of transcription and
replication during the viral life cycle. In addition to these conserved functions, we show that …

[HTML][HTML] Large scale genotype comparison of human papillomavirus E2-host interaction networks provides new insights for e2 molecular functions

M Muller, Y Jacob, L Jones, A Weiss, L Brino… - PLoS …, 2012 - journals.plos.org
Human Papillomaviruses (HPV) cause widespread infections in humans, resulting in latent
infections or diseases ranging from benign hyperplasia to cancers. HPV-induced …

[HTML][HTML] Tumor suppressor or oncogene? A critical role of the human papillomavirus (HPV) E2 protein in cervical cancer progression

S Bellanger, CL Tan, YZ Xue, S Teissier… - American journal of …, 2011 - ncbi.nlm.nih.gov
The papillomavirus (PV) E2 proteins have been shown to exert many functions in the viral
cycle including pivotal roles in transcriptional regulation and in viral DNA replication …

Characterization of novel bovine papillomavirus type 12 (BPV-12) causing epithelial papilloma

W Zhu, J Dong, E Shimizu, S Hatama, K Kadota… - Archives of …, 2012 - Springer
Abstract Bovine papillomavirus type 12 (BPV-12, putative type BAA1) was detected in
epithelial papilloma located on the tongue of an infected cow. Then, the whole genome was …