Engineered living materials for advanced diseases therapy

X Dong, W Wu, P Pan, XZ Zhang - Advanced Materials, 2023 - Wiley Online Library
Natural living materials serving as biotherapeutics exhibit great potential for treating various
diseases owing to their immunoactivity, tissue targeting, and other biological activities. In this …

[HTML][HTML] Outer Membrane Vesicles (OMVs) as Biomedical Tools and Their Relevance as Immune-Modulating Agents against H. pylori Infections: Current Status and …

AAQ Ahmed, R Besio, L Xiao, A Forlino - International Journal of …, 2023 - mdpi.com
Outer membrane vesicles (OMVs) are lipid-membrane-bounded nanoparticles that are
released from Gram-negative bacteria via vesiculation of the outer membrane. They have …

Role of extracellular vesicles in immunity and host defense

P Kumari, SS Wright, VA Rathinam - Immunological Investigations, 2024 - Taylor & Francis
Extracellular vesicles (EVs) are membrane-bound structures released by cells and have
become significant players in immune system functioning, primarily by facilitating cell-to-cell …

Bacterial extracellular vesicles induced oxidative stress and mitophagy through mTOR pathways in colon cancer cells, HT-29: Implications for bioactivity

TR Marzoog, MS Jabir, S Ibraheem, SF Jawad… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Abstract Bacterial-extracellular-vesicles (BEVs) derived from Escherichia coli, strain-A5922,
were used as a therapeutic tool to treat colon cancer cells, HT-29. BEVs induced oxidative …

[HTML][HTML] Engineered bacterial outer membrane vesicles: a versatile bacteria-based weapon against gastrointestinal tumors

K Zheng, Y Feng, L Li, F Kong, J Gao, X Kong - Theranostics, 2024 - ncbi.nlm.nih.gov
Outer membrane vesicles (OMVs) are nanoscale lipid bilayer structures released by gram-
negative bacteria. They share membrane composition and properties with their originating …

Recent advances in therapeutic engineered extracellular vesicles

C Yao, H Zhang, C Wang - Nanoscale, 2024 - pubs.rsc.org
Extracellular vesicles (EVs) are natural particles secreted by living cells, which hold
significant potential for various therapeutic applications. Native EVs have specific …

Tumor cell membrane‐based vaccines: A potential boost for cancer immunotherapy

M Yang, J Zhou, L Lu, D Deng, J Huang, Z Tang… - …, 2024 - Wiley Online Library
Because therapeutic cancer vaccines can, in theory, eliminate tumor cells specifically with
relatively low toxicity, they have long been considered for application in repressing cancer …

[HTML][HTML] Tumor Microenvironment Regulation and Cancer Targeting Therapy Based on Nanoparticles

S Han, Y Chi, Z Yang, J Ma, L Wang - Journal of Functional Biomaterials, 2023 - mdpi.com
Although we have made remarkable achievements in cancer awareness and medical
technology, there are still tremendous increases in cancer incidence and mortality. However …

[HTML][HTML] The potential role of gut microbiota outer membrane vesicles in colorectal cancer

R Meng, M Zeng, Y Ji, X Huang, M Xu - Frontiers in Microbiology, 2023 - frontiersin.org
Colorectal cancer (CRC) is a common malignant digestive tract tumor in colorectal regions.
Considerable evidence now shows that the gut microbiota have essential roles in CRC …

[HTML][HTML] Bacterial outer membrane vesicles as drug delivery carrier for photodynamic anticancer therapy

Y Jiang, ZZ Zhou, C Liu, L Wang, C Li - Frontiers in Chemistry, 2023 - ncbi.nlm.nih.gov
Photodynamic Therapy (PDT) is an effective tumor treatment strategy that not only induces
photocytotoxicity to kill tumor cells directly but also activates the immune system in the body …