T follicular helper (Tfh) cells with the phenotype of mainly expressing surface molecules
CXC motif chemokine receptor type 5 (CXCR5), inducible co-stimulator (ICOS), secreting …

Head and neck squamous cell carcinoma (HNSCC) is a common malignant tumour. Despite
advancements in surgery, radiotherapy and chemotherapy, which have improved the …

Systemic sclerosis (SSc) is a chronic systemic disease within the spectrum of connective
tissue diseases, specifically characterized by vascular abnormalities and inflammatory and …

Abstract Objectives Familial Mediterranean Fever (FMF) is the most common hereditary
monogenic fever syndrome that is characterized by recurrent attacks of fever and …

Abstract Background Coronavirus disease 2019 (COVID-19) induces a dysfunctional
immune response, inflammation, autoantibody production, and coagulopathy, which are …

Background m6A regulators have important roles in a variety of autoimmune diseases, but
their potential function in scleroderma, a refractory connective tissue disease, remains …

Systemic sclerosis (SSc) is an immune-mediated disease wherein T cells are particularly
implicated, presenting a poor prognosis and limited therapeutic options. Thus, mesenchymal …

This study investigated the role of IL-35 in systemic sclerosis (SSc) patients, focusing on
CD4+ T cell response and immunomodulatory cytokine production. By comparing the …

Systemic sclerosis is a connective tissue disease of unknown origin and with an
unpredictable course, with both cutaneous and internal organ manifestations. Despite the …

A systemic and local inflammatory immune imbalance is thought to be the cause of traumatic
tracheal stenosis (TS). However, with CD4+ T lymphocytes being the predominant immune …