Melatonin possesses the indoleamine structure and exerts antioxidant and anti-inflammatory
actions and other physiological properties. Physical exercise can influence secretion of …

Osteoarthritis (OA), characterized by cartilage erosion, synovium inflammation, and
subchondral bone remodeling, is a common joint degenerative disease worldwide. OA …

Osteoarthritis is the most common musculoskeletal disease causing chronic disability in
adults. Studying cartilage aging, chondrocyte senescence, inflammation, and autophagy …

Bone‑related diseases comprise a large group of common diseases, including fractures,
osteoporosis and osteoarthritis (OA), which affect a large number of individuals, particularly …

Osteoarthritis (OA), the most common arthritis worldwide, is a degenerative joint disease
characterized by progressive cartilage breakdown, subchondral remodeling, and synovial …

Purpose Bone diseases account for an enormous cost burden on health systems. Bone
disorders are considered as age-dependent diseases. The aging of world population has …

Melatonin's therapeutic potential has been highly underestimated because its biological
functional roles are diverse and relevant mechanisms are complicated. Among the …

The aim of the work is a literature review of published clinical studies on the effects of
hyperuricemia on the course of chronic heart failure (CHF). Results. High levels of uric acid …

Osteoarthritis (OA) is the most common age-related joint disease, affecting articular cartilage
and other joint structures, causing severe pain and disability. Due to a limited understanding …

Background The purpose of this study was to explore whether moderate-intensity exercise
can alleviate motion-induced post-traumatic osteoarthritis (PTOA) and the expression …