[HTML][HTML] Human iPSC banking: barriers and opportunities
CY Huang, CL Liu, CY Ting, YT Chiu… - Journal of biomedical …, 2019 - Springer
The introduction of induced pluripotent stem cells (iPSCs) has opened up the potential for
personalized cell therapies and ushered in new opportunities for regenerative medicine …
personalized cell therapies and ushered in new opportunities for regenerative medicine …
[HTML][HTML] Best practices for translational disease modeling using human iPSC-derived neurons
SJ Engle, L Blaha, RJ Kleiman - Neuron, 2018 - cell.com
From the beginning, induced pluripotent stem cell (iPSC) technology was touted as a path to
improve our understanding of disease biology and enable drug discovery. Advances in …
improve our understanding of disease biology and enable drug discovery. Advances in …
[HTML][HTML] The cellosaurus, a cell-line knowledge resource
A Bairoch - Journal of biomolecular techniques: JBT, 2018 - ncbi.nlm.nih.gov
The Cellosaurus is a knowledge resource on cell lines. It aims to describe all cell lines used
in biomedical research. Its scope encompasses both vertebrates and invertebrates …
in biomedical research. Its scope encompasses both vertebrates and invertebrates …
Souporcell: robust clustering of single-cell RNA-seq data by genotype without reference genotypes
Methods to deconvolve single-cell RNA-sequencing (scRNA-seq) data are necessary for
samples containing a mixture of genotypes, whether they are natural or experimentally …
samples containing a mixture of genotypes, whether they are natural or experimentally …
Expression Atlas: gene and protein expression across multiple studies and organisms
I Papatheodorou, NA Fonseca, M Keays… - Nucleic acids …, 2018 - academic.oup.com
Abstract Expression Atlas (http://www. ebi. ac. uk/gxa) is an added value database that
provides information about gene and protein expression in different species and contexts …
provides information about gene and protein expression in different species and contexts …
Gruffi: an algorithm for computational removal of stressed cells from brain organoid transcriptomic datasets
Á Vértesy, OL Eichmüller, J Naas… - The EMBO …, 2022 - embopress.org
Organoids enable in vitro modeling of complex developmental processes and disease
pathologies. Like most 3D cultures, organoids lack sufficient oxygen supply and therefore …
pathologies. Like most 3D cultures, organoids lack sufficient oxygen supply and therefore …
Locus-specific expression of transposable elements in single cells with CELLO-seq
Transposable elements (TEs) regulate diverse biological processes, from early development
to cancer. Expression of young TEs is difficult to measure with next-generation, single-cell …
to cancer. Expression of young TEs is difficult to measure with next-generation, single-cell …
[HTML][HTML] Large-scale profiling reveals the influence of genetic variation on gene expression in human induced pluripotent stem cells
In this study, we used whole-genome sequencing and gene expression profiling of 215
human induced pluripotent stem cell (iPSC) lines from different donors to identify genetic …
human induced pluripotent stem cell (iPSC) lines from different donors to identify genetic …
[HTML][HTML] iPSCORE: a resource of 222 iPSC lines enabling functional characterization of genetic variation across a variety of cell types
Large-scale collections of induced pluripotent stem cells (iPSCs) could serve as powerful
model systems for examining how genetic variation affects biology and disease. Here we …
model systems for examining how genetic variation affects biology and disease. Here we …
Dosage analysis of the 7q11.23 Williams region identifies BAZ1B as a major human gene patterning the modern human face and underlying self-domestication
We undertook a functional dissection of chromatin remodeler BAZ1B in neural crest (NC)
stem cells (NCSCs) from a uniquely informative cohort of typical and atypical patients …
stem cells (NCSCs) from a uniquely informative cohort of typical and atypical patients …