Changes in glycolytic pathway in SARS-COV 2 infection and their importance in understanding the severity of COVID-19

AF Santos, P Póvoa, P Paixão, A Mendonça… - Frontiers in …, 2021 - frontiersin.org
COVID-19 is an infectious disease caused by Coronavirus 2 (SARS-CoV-2) that may lead to
a severe acute respiratory syndrome. Such syndrome is thought to be related, at least in …

COVID-19: comprehensive review on mutations and current vaccines

AV Hebbani, S Pulakuntla, P Pannuru… - Archives of …, 2022 - Springer
Viral outbreaks had been a threat for the human race for a long time. Several epidemics and
pandemics have been reported in the past with serious consequences on human health and …

Identification of RdRp inhibitors against SARS-CoV-2 through E-pharmacophore-based virtual screening, molecular docking and MD simulations approaches

HM Rehman, M Sajjad, MA Ali, R Gul, M Naveed… - International Journal of …, 2023 - Elsevier
The outbreak of novel Coronavirus, an enduring pandemic declared by WHO, has
consequences to an alarming ongoing public health menace which has already claimed …

Role of medicinal plants in inhibiting SARS-CoV-2 and in the management of post-COVID-19 complications

PK Mukherjee, T Efferth, B Das, A Kar, S Ghosh… - Phytomedicine, 2022 - Elsevier
Background The worldwide corona virus disease outbreak, generally known as COVID-19
pandemic outbreak resulted in a major health crisis globally. The morbidity and transmission …

Potential anti-SARS-CoV-2 prodrugs activated by phosphorylation and their role in the aged population

VP Chavda, D Teli, PC Balar, D Vaghela, HK Solanki… - Molecules, 2023 - mdpi.com
The COVID-19 pandemic has flared across every part of the globe and affected populations
from different age groups differently. People aged from 40 to 80 years or older are at an …

2-Deoxy-D-Glucose and its derivatives for the COVID-19 treatment: an update

Z Huang, VP Chavda, LK Vora, N Gajjar… - Frontiers in …, 2022 - frontiersin.org
Treatment choices for the “severe acute respiratory syndrome‐related coronavirus‐2 (SARS‐
CoV‐2)” are inadequate, having no clarity on efficacy and safety profiles. Currently, no …

Integrated multi-omics reveals the activated retinal microglia with intracellular metabolic reprogramming contributes to inflammation in STZ-induced early diabetic …

K Lv, H Ying, G Hu, J Hu, Q Jian, F Zhang - Frontiers in Immunology, 2022 - frontiersin.org
Diabetic retinopathy (DR) is the leading cause of visual impairment and blindness among
working-age people. Inflammation is recognized as a critical driver of the DR process …

Technological advancements in external beam radiation therapy (EBRT): An indispensable tool for cancer treatment

K Koka, A Verma, BS Dwarakanath… - Cancer Management …, 2022 - Taylor & Francis
Recent technological advancements have increased the efficacy of radiotherapy, leading to
effective management of cancer patients with enhanced patient survival and improved …

SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis

J Zhu, G Wang, X Huang, H Lee, JG Lee… - Communications …, 2022 - nature.com
SARS-CoV-2 infection causes COVID-19, a severe acute respiratory disease associated
with cardiovascular complications including long-term outcomes. The presence of virus in …

PPAR ligands induce antiviral effects targeting perturbed lipid metabolism during SARS-CoV-2, HCV, and HCMV infection

M Fantacuzzi, R Amoroso, A Ammazzalorso - Biology, 2022 - mdpi.com
Simple Summary The current coronavirus disease 2019 pandemic turned the attention of
researchers to developing novel strategies to counteract virus infections. Despite several …