Non-coding RNAs in disease: from mechanisms to therapeutics

K Nemeth, R Bayraktar, M Ferracin… - Nature Reviews Genetics, 2024 - nature.com
Non-coding RNAs (ncRNAs) are a heterogeneous group of transcripts that, by definition, are
not translated into proteins. Since their discovery, ncRNAs have emerged as important …

Wearable and miniaturized sensor technologies for personalized and preventive medicine

A Tricoli, N Nasiri, S De - Advanced Functional Materials, 2017 - Wiley Online Library
The unprecedented medical achievements of the last century have dramatically improved
our quality of life. Today, the high cost of many healthcare approaches challenges their long …

MicroRNAome genome: a treasure for cancer diagnosis and therapy

I Berindan‐Neagoe, PC Monroig… - CA: a cancer journal …, 2014 - Wiley Online Library
The interplay between abnormalities in genes coding for proteins and noncoding
microRNAs (miRNAs) has been among the most exciting yet unexpected discoveries in …

MicroRNAs in development and disease

D Sayed, M Abdellatif - Physiological reviews, 2011 - journals.physiology.org
MicroRNAs (miRNAs) are a class of posttranscriptional regulators that have recently
introduced an additional level of intricacy to our understanding of gene regulation. There are …

miRCancer: a microRNA–cancer association database constructed by text mining on literature

B Xie, Q Ding, H Han, D Wu - Bioinformatics, 2013 - academic.oup.com
Motivation: Research interests in microRNAs have increased rapidly in the past decade.
Many studies have showed that microRNAs have close relationships with various human …

Physiological and pathological roles for microRNAs in the immune system

RM O'connell, DS Rao, AA Chaudhuri… - Nature Reviews …, 2010 - nature.com
Mammalian microRNAs (miRNAs) have recently been identified as important regulators of
gene expression, and they function by repressing specific target genes at the post …

MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts

T Thum, C Gross, J Fiedler, T Fischer, S Kissler… - Nature, 2008 - nature.com
MicroRNAs comprise a broad class of small non-coding RNAs that control expression of
complementary target messenger RNAs,. Dysregulation of microRNAs by several …

[HTML][HTML] Regulatory mechanisms of epigenetic miRNA relationships in human cancer and potential as therapeutic targets

KMT Arif, EK Elliott, LM Haupt, LR Griffiths - Cancers, 2020 - mdpi.com
Simple Summary By the virtue of targeting multiple genes, a microRNA (miRNA) can infer
variable consequences on tumorigenesis by appearing as both a tumour suppressor and …

MicroRNAs in cancer

YS Lee, A Dutta - Annual Review of Pathology: Mechanisms of …, 2009 - annualreviews.org
Within the past few years, studies on microRNA (miRNA) and cancer have burst onto the
scene. Profiling of the miRNome (global miRNA expression levels) has become prevalent …

[HTML][HTML] Detection of microRNA expression in human peripheral blood microvesicles

MP Hunter, N Ismail, X Zhang, BD Aguda, EJ Lee, L Yu… - PloS one, 2008 - journals.plos.org
Background MicroRNAs (miRNA) are small non-coding RNAs that regulate translation of
mRNA and protein. Loss or enhanced expression of miRNAs is associated with several …