Long-acting HIV pre-exposure prophylaxis (PrEP) approaches: recent advances, emerging technologies, and development challenges

V Agrahari, SM Anderson, MM Peet… - Expert opinion on …, 2022 - Taylor & Francis
Introduction Poor or inconsistent adherence to daily oral pre-exposure prophylaxis (PrEP)
has emerged as a key barrier to effective HIV prevention. The advent of potent long-acting …

[HTML][HTML] Preexposure prophylaxis for prevention of HIV acquisition among adolescents: clinical considerations, 2020

MR Tanner - MMWR. Recommendations and Reports, 2020 - cdc.gov
Preexposure prophylaxis (PrEP) with antiretroviral medication has been proven effective in
reducing the risk for acquiring human immunodeficiency virus (HIV). The fixed-dose …

Efficacy estimates of oral pre-exposure prophylaxis for HIV prevention in cisgender women with partial adherence

M Moore, S Stansfield, DJ Donnell, MC Boily… - Nature medicine, 2023 - nature.com
Pre-exposure prophylaxis (PrEP) with tenofovir (TFV) disoproxil fumarate and emtricitabine
administered orally daily is effective in preventing human immunodeficiency virus (HIV) …

Uptake of HIV preexposure prophylaxis among commercially insured persons—United States, 2010–2014

H Wu, MCB Mendoza, YA Huang… - Clinical Infectious …, 2017 - academic.oup.com
Background. Daily, oral use of tenofovir disoproxil fumarate and emtricitabine (TDF-FTC) for
preexposure prophylaxis (PrEP) is an effective strategy to prevent acquisition of human …

How acceptable are antiretrovirals for the prevention of sexually transmitted HIV?: A review of research on the acceptability of oral pre-exposure prophylaxis and …

I Young, L McDaid - AIDS and Behavior, 2014 - Springer
Recent research has demonstrated how antiretrovirals (ARVs) could be effective in the
prevention of sexually transmitted HIV. We review research on the acceptability of oral pre …

The promise of improved adherence with long-acting antiretroviral therapy: what are the data?

KK Scarsi, S Swindells - … of Providers of AIDS Care (JIAPAC), 2021 - journals.sagepub.com
As with other chronic conditions, adherence to daily medications remains a challenge for
many individuals living with HIV due to structural, behavioral, and social barriers …

High pre‐exposure prophylaxis uptake and early adherence among men who have sex with men and transgender women at risk for HIV Infection: the PrEP Brasil …

B Hoagland, RI Moreira, RB De Boni… - Journal of the …, 2017 - Wiley Online Library
Introduction: The efficacy of pre‐exposure prophylaxis (PrEP) in preventing sexual
acquisition of human immunodeficiency virus (HIV) is well established. Little is known about …

Pre‐exposure prophylaxis initiation and adherence among Black men who have sex with men (MSM) in three US cities: results from the HPTN 073 study

DP Wheeler, SD Fields, G Beauchamp… - Journal of the …, 2019 - Wiley Online Library
Introduction Randomized clinical trials have demonstrated the efficacy of antiretroviral pre‐
exposure prophylaxis (Pr EP) in preventing HIV acquisition among men who have sex with …

A tale of two viruses: immunological insights into HCV/HIV coinfection

ST Gobran, P Ancuta, NH Shoukry - Frontiers in immunology, 2021 - frontiersin.org
Nearly 2.3 million individuals worldwide are coinfected with human immunodeficiency virus
(HIV) and hepatitis C virus (HCV). Odds of HCV infection are six times higher in people living …

How has HIV pre-exposure prophylaxis (PrEP) changed sex? A review of research in a new era of bio-behavioral HIV prevention

C Grov, DA Westmoreland, AB D'Angelo… - The Journal of Sex …, 2021 - Taylor & Francis
In 2012, the US FDA approved the first drug for use as HIV Pre-Exposure Prophylaxis
(PrEP), which is nearly 99% effective when taken as prescribed. Although the manifest …