Development and challenges of antimicrobial peptide delivery strategies in bacterial therapy: A review

L Yao, Q Liu, Z Lei, T Sun - International Journal of Biological …, 2023 - Elsevier
The escalating global prevalence of antimicrobial resistance poses a critical threat,
prompting concerns about its impact on public health. This predicament is exacerbated by …

Perspectives in searching antimicrobial peptides (AMPs) produced by the microbiota

L Gallardo-Becerra, M Cervantes-Echeverría… - Microbial Ecology, 2024 - Springer
Abstract Changes in the structure and function of the microbiota are associated with various
human diseases. These microbial changes can be mediated by antimicrobial peptides …

Creation of new antimicrobial peptides

OV Galzitskaya - International Journal of Molecular Sciences, 2023 - mdpi.com
Antimicrobial peptides (AMPs) are natural compounds that exhibit potent antimicrobial
activity against various microorganisms, including bacteria, fungi, and viruses. However, the …

[HTML][HTML] Non-toxic antimicrobial peptide Hm-AMP2 from leech metagenome proteins identified by the gradient-boosting approach

EN Grafskaia, ER Pavlova, IA Latsis, MV Malakhova… - Materials & Design, 2022 - Elsevier
The number of infections caused by antibiotic-resistant pathogens is increasing alarmingly
every year and will continue to grow. Antimicrobial peptides (AMPs) are considered new …

Identification and Characterization of RK22, a Novel Antimicrobial Peptide from Hirudinaria manillensis against Methicillin Resistant Staphylococcus aureus

X Lu, M Yang, S Zhou, S Yang, X Chen… - International Journal of …, 2023 - mdpi.com
Staphylococcus aureus (S. aureus) infections are a leading cause of morbidity and mortality,
which are compounded by drug resistance. By manipulating the coagulation system, S …

Effects of medicinal leech-related cationic antimicrobial peptides on human blood cells and plasma

TV Vakhrusheva, GD Moroz, LY Basyreva… - Molecules, 2022 - mdpi.com
Cationic antimicrobial peptides (CAMPs) are considered as next-generation antibiotics with
a lower probability of developing bacterial resistance. In view of potential clinical use …

Effects of synthetic short cationic antimicrobial peptides on the catalytic activity of myeloperoxidase, reducing its oxidative capacity

TV Vakhrusheva, AV Sokolov, GD Moroz, VA Kostevich… - Antioxidants, 2022 - mdpi.com
Cationic antimicrobial peptides (CAMPs) have gained attention as promising antimicrobial
therapeutics causing lower or no bacterial resistance. Considerable achievements have …

High-Throughput Sequencing Reveals the Effect of Feeding on Overwintering Hirudo nipponia

H Shen, M Cai, J Li, Y Luo - Diversity, 2022 - mdpi.com
To investigate the effect of feeding on hibernating Hirudo nipponia, metagenomic
sequencing was performed on the microorganisms collected from the digestive tract of H …

Therapeutic effects of synthetic triblock amphiphilic short antimicrobial peptides on human lung adenocarcinoma

D Yang, L Zhu, X Lin, J Zhu, Y Qian, W Liu, J Chen… - Pharmaceutics, 2022 - mdpi.com
Because of their unique properties, antimicrobial peptides (AMPs) represent a potential
reservoir of novel anticancer therapeutic agents. However, only a few AMPs can kill tumors …

Systematic review of medicinal leech therapy in urology

AO Battin, N Hobeika, MJ Zdilla - African Journal of Urology, 2023 - Springer
Background Medicinal leech therapy, otherwise known as hirudotherapy or leeching, has
been utilized for numerous pathologies over centuries. The technique resurfaced in modern …