[HTML][HTML] Retina as a potential biomarker in schizophrenia spectrum disorders: a systematic review and meta-analysis of optical coherence tomography and …

H Komatsu, G Onoguchi, SM Silverstein, S Jerotic… - Molecular …, 2024 - nature.com
Introduction Abnormal findings on optical coherence tomography (OCT) and
electroretinography (ERG) have been reported in participants with schizophrenia spectrum …

[HTML][HTML] Next-generation cognitive assessment: combining functional brain imaging, system perturbations and novel equipment interfaces

PA Hall, AM Burhan, JC McKillop, D Duarte - Brain Research Bulletin, 2023 - Elsevier
Conventional cognitive assessment is widely used in clinical and research settings,
educational institutions, and the corporate world for personnel selection. Such approaches …

[HTML][HTML] Machine-learning-based models to predict cardiovascular risk using oculomics and clinic variables in KNHANES

Y Zhang, S Li, W Wu, Y Zhao, J Han, C Tong, N Luo… - BioData Mining, 2024 - Springer
Background Recent researches have found a strong correlation between the triglyceride-
glucose (TyG) index or the atherogenic index of plasma (AIP) and cardiovascular disease …

[HTML][HTML] Intravitreal MPTP drives retinal ganglion cell loss with oral nicotinamide treatment providing robust neuroprotection

A Rombaut, D Jovancevic, RCB Wong, A Nicol… - Acta Neuropathologica …, 2024 - Springer
Neurodegenerative diseases have common underlying pathological mechanisms including
progressive neuronal dysfunction, axonal and dendritic retraction, and mitochondrial …

Association between polygenic risk for schizophrenia and retinal morphology: A cross-sectional analysis of the United Kingdom Biobank

BA Blose, SM Silverstein, KV Stuart, PA Keane… - Psychiatry …, 2024 - Elsevier
We examined the relationship between genetic risk for schizophrenia (SZ), using polygenic
risk scores (PRSs), and retinal morphological alterations. Retinal structural and vascular …

Structural correlations between brain magnetic resonance image‐derived phenotypes and retinal neuroanatomy

Z Sun, B Zhang, S Smith, D Atan… - European Journal of …, 2024 - Wiley Online Library
Background and purpose The eye is a well‐established model of brain structure and
function, yet region‐specific structural correlations between the retina and the brain remain …

[HTML][HTML] Optometry in adults with microdeletion 22q11. 2: The eye as a window to the brain

ENMM von Scheibler, A Appaji… - Biomarkers in …, 2023 - Elsevier
Abstract Purpose The 22q11. 2 deletion syndrome (22q11. 2DS) has an estimated
prevalence of 1: 2148 live births and is associated with an increased risk of schizophrenia …

[HTML][HTML] Oculomics: A Crusade Against the Four Horsemen of Chronic Disease

EJ Patterson, AD Bounds, SK Wagner… - Ophthalmology and …, 2024 - Springer
Chronic, non-communicable diseases present a major barrier to living a long and healthy
life. In many cases, early diagnosis can facilitate prevention, monitoring, and treatment …

Specific association between retinal neural layer thinning and neurological soft signs in schizophrenia

P Krukow, A Domagała, SM Silverstein - European Archives of Psychiatry …, 2024 - Springer
There is growing evidence of disproportionate retinal thinning in schizophrenia, but doubts
are still raised regarding its significance in the context of the neurobiology of the disease …

[HTML][HTML] Signature of altered retinal microstructures and electrophysiology in schizophrenia spectrum disorders is associated with disease severity and polygenic risk

E Boudriot, V Gabriel, D Popovic, P Pingen… - Biological …, 2024 - Elsevier
BACKGROUND Optical coherence tomography (OCT) and electroretinography (ERG)
studies have revealed structural and functional retinal alterations in individuals with …