[HTML][HTML] Neisseria gonorrhoeae host adaptation and pathogenesis

SJ Quillin, HS Seifert - Nature Reviews Microbiology, 2018 - nature.com
The urogenital tract is a complex environment composed of many different types of epithelial
tissues and innate immune cells that sample the surrounding milieu. As a host-adapted …

Cellular mechanisms and molecular pathways linking bitter taste receptor signalling to cardiac inflammation, oxidative stress, arrhythmia and contractile dysfunction in …

MO Welcome, D Dogo, NE Mastorakis - Inflammopharmacology, 2023 - Springer
Heart diseases and related complications constitute a leading cause of death and
socioeconomic threat worldwide. Despite intense efforts and research on the pathogenetic …

Neisseria gonorrhoeae MlaA influences gonococcal virulence and membrane vesicle production

BI Baarda, RA Zielke, A Le Van, AE Jerse… - Plos …, 2019 - journals.plos.org
The six-component maintenance of lipid asymmetry (Mla) system is responsible for
retrograde transport of phospholipids, ensuring the barrier function of the Gram-negative cell …

Microbial degradation of forensic samples of biological origin: potential threat to human DNA typing

HR Dash, S Das - Molecular biotechnology, 2018 - Springer
Forensic biology is a sub-discipline of biological science with an amalgam of other branches
of science used in the criminal justice system. Any nucleated cell/tissue harbouring DNA …

Characterization and in vitro evaluation of a vaginal gel containing Lactobacillus crispatus for the prevention of gonorrhea

KCNG Gnaman, S Bouttier, A Yeo… - International Journal of …, 2020 - Elsevier
The increasing resistance of Neisseria gonorrhoeae to any current antibiotic treatment and
the difficulties associated with the use of prevention means such as condom urge the need …

Semen microbiota and cytokines of healthy and infertile men

OV Bukharin, NB Perunova, EV Ivanova… - Asian Journal of …, 2022 - journals.lww.com
In this study, we determined the levels of cytokine secretory inhibitors and the microbiota
biofilms of semen from healthy and infertile subjects. A total of 118 clinical bacterial isolates …

The bitterness of genitourinary infections: Properties, ligands of genitourinary bitter taste receptors and mechanisms linking taste sensing to inflammatory processes in …

MO Welcome - European Journal of Obstetrics & Gynecology and …, 2020 - Elsevier
Background Though, first identified in the gastrointestinal tract, bitter taste receptors are now
believed to be ubiquitously expressed in several regions of the body, including the …

Anti-Virulence Therapeutic Approaches for Neisseria gonorrhoeae

KYL Lim, CA Mullally, EC Haese, EA Kibble… - Antibiotics, 2021 - mdpi.com
While antimicrobial resistance (AMR) is seen in both Neisseria gonorrhoeae and Neisseria
meningitidis, the former has become resistant to commonly available over-the-counter …

Emerging threat of antimicrobial resistance in Neisseria gonorrhoeae: pathogenesis, treatment challenges, and potential for vaccine development

UNM Omeershffudin, S Kumar - Archives of Microbiology, 2023 - Springer
The continuous rise of antimicrobial resistance (AMR) is a serious concern as it endangers
the effectiveness of healthcare interventions that rely on antibiotics in the long run. The …

Adherence Enables Neisseria gonorrhoeae to Overcome Zinc Limitation Imposed by Nutritional Immunity Proteins

JC Ray, A Smirnov, SA Maurakis… - Infection and …, 2022 - Am Soc Microbiol
Neisseria gonorrhoeae (Gc) must overcome the limitation of metals such as zinc to colonize
mucosal surfaces in its obligate human host. While the zinc-binding nutritional immunity …