Psychedelics, recognized for their impact on perception, are resurging as promising
treatments with rapid onset for mood and substance use disorders. Despite increasing …

Importance Adolescent depression is characterized by diverse symptom trajectories over
time and has a strong genetic influence. Research has determined genetic overlap between …

A detailed investigation into the mechanistic course of N-hydroxyphthalimide catalyzed
oxidation of benzylic centers using sodium chlorite as the stoichiometric oxidant is reported …

Single-cell technologies have enhanced comprehensive knowledge regarding the human
brain by facilitating an extensive transcriptomic census across diverse brain regions …

Using Medical Records to Investigate the Genetics of Treatment-Resistant Depression
Across Health Care Systems Using Medical Records to Investigate the Genetics of …

In a genome-wide association study (GWAS) meta-analysis of 685,808 individuals with
major depression (MD) and 4,364,225 controls from 29 countries and across diverse and …

Background and aims: There is growing evidence that tobacco smoking causes depression,
but it is unclear which constituents of tobacco smoke (eg, nicotine, carbon monoxide) may …

Translating genetic findings for neurodevelopmental and psychiatric disorders (NPD) into
actionable disease biology would benefit from large-scale and unbiased functional studies …

Background: Genome-wide association studies (GWAS) of depression typically rely on cross-
sectional designs, using lifetime history (LTH) of a diagnosis as the primary outcome. While …

This investigation elucidates the genetic connection between major depressive disorder
(MD) and metabolic syndrome (MetS), uncovering bidirectional interactions and shared …