Mitochondria play a major role in ROS production and defense during their life cycle. The
transcriptional activator PGC-1α is a key player in the homeostasis of energy metabolism …

Red cell diseases encompass a group of inherited or acquired erythrocyte disorders that
affect the structure, function, or production of red blood cells (RBCs). These disorders can …

Thyroid diseases, including neoplasms, autoimmune diseases and thyroid dysfunctions, are
becoming a serious social problem with rapidly increasing prevalence. The latter is …

Amyotrophic lateral sclerosis (ALS) is a rapidly debilitating fatal neurodegenerative disorder,
causing muscle atrophy and weakness, which leads to paralysis and eventual death. ALS …

Simple Summary There is no doubt that the need for new effective methods of cancer
treatment remains challenging, as cancer is the second cause of death based on the …

Abstract World Health Organisation (WHO) delineated cancer as one of the foremost
reasons for mortality with 10 million deaths in the year 2020. Early diagnosis and effective …

Oxidation modulators regarding antioxidants and reactive oxygen species (ROS) inducers
have been used for the treatment of many diseases. However, a systematic review that …

Acquired platinum resistance poses a significant therapeutic impediment to ovarian cancer
patient care, accounting for more than 200,000 deaths annually worldwide. We previously …

Coronary ischemia-reperfusion (IR) injury results from a blockage of blood supply to the
heart followed by restoration of perfusion, leading to oxidative stress induced pathological …

Alcoholic liver disease (ALD) is a major worldwide chronic liver disease accompanied by
hepatic inflammation, gut leakiness, and abnormal oxidative stress. Our previous study …