Peptides and drug delivery

KR Ulapane, BM Kopec, MEG Moral… - Peptides and peptide …, 2017 - Springer
Peptides have been used as drugs to treat various health conditions, and they are also
being developed as diagnostic agents. Due to their receptor selectivity, peptides have …

Novel IL-2-Poly (HPMA) nanoconjugate based immunotherapy

P Votavova, J Tomala, V Subr… - Journal of …, 2015 - ingentaconnect.com
Interleukin-2 (IL-2) possesses a strong stimulatory activity for activated T and NK cells and it
is an attractive molecule for immunotherapy. Nevertheless, extremely short half-life and …

Synthesis and characterization of quaternary phosphonium-containing, trithiocarbonate RAFT agents

L Zhang, Q Tang, RA Weiss, KA Cavicchi - Polymer Chemistry, 2014 - pubs.rsc.org
In this article the syntheses of quaternary phosphonium-containing trithiocarbonate RAFT
agents (RAFT-PR3, R= Bu and Ph) and their use in the bulk, thermally initiated …

Novel Malachite Green-and Rhodamine B-labeled cationic chain transfer agents for RAFT polymerization

M Beija, CAM Afonso, JPS Farinha, MT Charreyre… - Polymer, 2011 - Elsevier
Two novel cationic RAFT agents have been synthesized, one labeled with a Malachite
Green (MG) dye and another with a Rhodamine B (RhoB) dye. MG-labeled dithiobenzoate …

A cancer-targetable copolymer containing tyrosine segments for labeling radioactive halogens

Y Qi, N Li, Q Xu, X Xia, J Ge, J Lu - Reactive and Functional Polymers, 2011 - Elsevier
A series of cancer-targetable copolymers containing rhodamine and tyrosine segments were
synthesized and further labeled with isotope 125I. Copolymers with different molecular …

Can QSAR models describing small-molecule xenobiotics give useful tips for predicting uptake and localization of nanoparticles in living cells? And if not, why not?

RW Horobin - Organelle-specific pharmaceutical …, 2010 - books.google.com
Nanoparticles come with a wide variety of composition and form, and possess a wide variety
of surface features. When considering their biomedical applications, cellular uptake and …

Multifunctional water-soluble polymers for drug delivery

H Pan, J Kopecek - Multifunctional pharmaceutical nanocarriers, 2008 - Springer
Water-soluble polymer–drug conjugates are multifunctional nanomedicines at the interface
of polymer chemistry and biomedical sciences. Advances in chemistry and applied biology …

Antitumor activity and antitumor mechanism of triphenylphosphonium chitosan against liver carcinoma

H Huang, H Wu, Y Huang, S Zhang… - Journal of Materials …, 2018 - cambridge.org
N-(3-Carboxypropyl) triphenylphosphonium bromide chitosan (TPPB-CS) was synthesized
and characterized by FTIR, 1H NMR spectrometer, and Zeta potential. TPPB-CS showed a …

纳米载体细胞器靶向的研究进展

孙晓, 魏丽丽, 陈海靓, 梁文权 - 药学学报, 2009 - cqvip.com
现代给药系统要求药物在充分发挥疗效的同时毒副作用小, 这就需要药物能被特异转运至靶组织
, 靶细胞. 甚至是特定的细胞器, 如细胞质基质, 细胞核, 线粒体, 溶酶体, 内质网等 …

Nanocarriers for cytosolic drug and gene delivery in cancer therapy

S Palakurthi, VK Yellepeddi… - … , Trends, Research and …, 2011 - books.google.com
In this burgeoning era of personalized medicine we have witnessed a humongous increase
in novel therapeutics encompassing wide range of modalities including small molecule …