Tumor mutational burden for predicting prognosis and therapy outcome of hepatocellular carcinoma

D Gabbia, S De Martin - International journal of molecular sciences, 2023 - mdpi.com
Hepatocellular carcinoma (HCC), the primary hepatic malignancy, represents the second-
highest cause of cancer-related death worldwide. Many efforts have been devoted to finding …

[HTML][HTML] N7-methylguanosine modification: from regulatory roles to therapeutic implications in cancer

M Cai, C Yang, Z Wang - American Journal of Cancer Research, 2023 - ncbi.nlm.nih.gov
Abstract N7-methylguanosine (m7G) is one of the most common post-transcriptional
epigenetic modifications. Different m7G methyltransferases (writers) load the m7G-cap at the …

Comprehensive multi-omics analysis of the m7G in pan-cancer from the perspective of predictive, preventive, and personalized medicine

X Huang, Z Chen, X Xiang, Y Liu, X Long, K Li, M Qin… - EPMA Journal, 2022 - Springer
Background The N7-methylguanosine modification (m7G) of the 5′ cap structure in the
mRNA plays a crucial role in gene expression. However, the relation between m7G and …

[HTML][HTML] Constructing and validating of m7G-related genes prognostic signature for hepatocellular carcinoma and immune infiltration: potential biomarkers for …

P Liu, C Dong, H Shi, Z Yan, J Zhang… - Journal of …, 2022 - ncbi.nlm.nih.gov
Background To investigate the prognostic significance of N7-methylguanosine (m7G)
regulators and immune infiltration in liver hepatocellular carcinoma (LIHC). Methods The …

Integrating single-cell and bulk sequencing data to identify glycosylation-based genes in non-alcoholic fatty liver disease-associated hepatocellular carcinoma

Z Zhou, Y Gao, L Deng, X Lu, Y Lai, J Wu, S Chen, C Li… - PeerJ, 2024 - peerj.com
Background The incidence of non-alcoholic fatty liver disease (NAFLD) associated
hepatocellular carcinoma (HCC) has been increasing. However, the role of glycosylation, an …

[HTML][HTML] M7G-related tumor immunity: novel insights of RNA modification and potential therapeutic targets

M Han, Q Huang, X Li, X Chen, H Zhu… - … Journal of Biological …, 2024 - ncbi.nlm.nih.gov
RNA modifications play a pivotal role in regulating cellular biology by exerting influence over
distribution features and molecular functions at the post-transcriptional level. Among these …

[HTML][HTML] Identification of N7-methylguanosine-related lncRNAs for the risk stratification of hepatocellular carcinoma

Y Li, K Zhao, R Wu, J Wang, Q Wang… - Journal of …, 2023 - ncbi.nlm.nih.gov
Background Hepatocellular carcinoma (HCC) is one of the most common malignancies in
the world. The N7-methylguanosine (m7G) modification is related to the biological …