The liver is a key organ that plays a pivotal role in metabolism and ensures a variety of
functions in the body, including homeostasis, synthesis of essential components, nutrient …

Abstract Organ-on-chip (OoC) platforms are a new class of advanced microfluidic devices
that have been attracting significant attention for drug development since they can allow a …

This study characterized the impact of post-weaning high-fat diet (HFD) and/or permethrin
(PER) treatment on heart dysfunction and fibrosis, as well as atherogenic risk, in rats by …

Several studies have reported a correlation between pesticides exposure and metabolic
disorders. Dichlorodiphenyltrichloroethane (DDT) and permethrin (PMT), two pesticides …

The pyrethroid insecticide, bifenthrin, is frequently measured at concentrations exceeding
those that induce acute and chronic toxicity to several invertebrate and fish species residing …

Abstract Background Permethrin and N, N-diethyl-meta-toluamide (DEET) are the pesticides
and insect repellent most commonly used by humans. These pesticides have been shown to …

Animal models are considered prime study models for inhalation-like toxicity assessment.
However, in light of animal experimentation reduction (3Rs), we developed and investigated …

Interactions between the different liver cell types are critical to the maintenance or induction
of their function in vitro. In this work, human-induced Pluripotent Stem Cells (hiPSCs) …

Despite the diversity of studies on pesticide toxicities, there is a serious lack of information
concerning the toxic effect of pesticides mixtures. Dichlorodiphenyl‐trichloroethane (DDT) …

This study is the first to examine the possible mechanism by which long-term exposure to
permethrin (PER) can promote arterial retention of proatherogenic lipid and lipoproteins and …