Gout is the most common form of inflammatory arthritis and is a multifactorial disease
typically characterized by hyperuricemia and monosodium urate crystal deposition …

Hyperuricemia and gout, the clinical manifestation of monosodium urate crystal deposition,
are common in patients with chronic kidney disease (CKD). Although the presence of CKD …

A simple dual-read assay for uric acid (UA) was developed based on a combined ratiometric
fluorescent and colorimetric strategy using nitrogen-doped carbon dots (N-CDs). The …

Importance Clinicians are often cautious about use of allopurinol in patients with gout when
renal function declines. Objective To assess the association of allopurinol use in gout with …

Allopurinol is the first-line medication for hyperuricemia treatment. However, severe drug-
related adverse effects have often been reported among patients who received allopurinol …

This study was aimed to investigate the hypouricemic effect of anthocyanins from purple
sweet potato in vivo and their possible interaction mechanism to xanthine oxidase (XO) in …

Background While the dose of allopurinol is limited in patients with chronic kidney disease
(CKD), information is lacking concerning the efficacy, safety, and maintenance dose of …

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Inhibiting tubular urate reabsorption may protect the kidney from urate-induced tubular
injury. However, this approach may promote intratubular uric acid crystallization, especially …

Background Mounting studies have shown that hyperuricemia is related to kidney diseases
through multiple ways. However, the application of urinary uric acid indicators in patients …