Cerebrospinal fluid biomarkers for understanding multiple aspects of Alzheimer's disease pathogenesis

K Dhiman, K Blennow, H Zetterberg, RN Martins… - Cellular and molecular …, 2019 - Springer
Alzheimer's disease (AD) is a multifactorial age-related brain disease. Numerous
pathological events run forth in the brain leading to AD. There is an initial long, dormant …

Oxidative stress and adult neurogenesis

TF Yuan, S Gu, C Shan, S Marchado… - Stem Cell Reviews and …, 2015 - Springer
There is a growing evidence that adult neurogenesis is critical for brain function. The
reactive oxygen species (ROS) is accumulated during adult neurogenesis as a physiological …

[HTML][HTML] Detection of Alzheimer's disease by displacement field and machine learning

Y Zhang, S Wang - PeerJ, 2015 - peerj.com
Aim. Alzheimer's disease (AD) is a chronic neurodegenerative disease. Recently, computer
scientists have developed various methods for early detection based on computer vision …

Detection of Alzheimer's disease by three-dimensional displacement field estimation in structural magnetic resonance imaging

S Wang, Y Zhang, G Liu, P Phillips… - Journal of Alzheimer's …, 2016 - content.iospress.com
Background: Within the past decade, computer scientists have developed many methods
using computer vision and machine learning techniques to detect Alzheimer's disease (AD) …

[HTML][HTML] Honokiol attenuates oligomeric amyloid β1-42-induced Alzheimer's disease in mice through attenuating mitochondrial apoptosis and inhibiting the nuclear …

M Wang, Y Li, C Ni, G Song - Cellular Physiology and Biochemistry, 2017 - karger.com
Background: Increasing evidence indicates that amyloid β oligomer (AβO) is toxic to neurons
in Alzheimer's disease (AD) brain. The aim of the present study is to evaluate the effects of …

Omega-3 polyunsaturated fatty acids promote brain-to-blood clearance of β-Amyloid in a mouse model with Alzheimer's disease

L Yan, Y Xie, SK Satyanarayanan, H Zeng, Q Liu… - Brain, Behavior, and …, 2020 - Elsevier
Amyloid-β (Aβ) plaques is one of the typical pathological hallmark of Alzheimer disease
(AD). Accumulating evidence suggests that the imbalance between Aβ production and …

Fish oil prevents lipopolysaccharide-induced depressive-like behavior by inhibiting neuroinflammation

Z Shi, H Ren, Z Huang, Y Peng, B He, X Yao… - Molecular …, 2017 - Springer
Depression is associated with somatic immune changes, and neuroinflammation is now
recognized as hallmark for depressive disorders. N-3 (or omega-3) polyunsaturated fatty …

[HTML][HTML] Probiotics: the next dietary strategy against brain aging

JS Ong, LC Lew, YY Hor, MT Liong - Preventive Nutrition and Food …, 2022 - ncbi.nlm.nih.gov
Owing to their long history of safe use, probiotic microorganisms, typically from the genus
Lactobacillus, have long been recognized, especially in traditional and fermented food …

Dioscin protects against Aβ1–42 oligomers-induced neurotoxicity via the function of SIRT3 and autophagy

Z Zhang, K Han, C Wang, C Sun, N Jia - … and Pharmaceutical Bulletin, 2020 - jstage.jst.go.jp
Alzheimer's disease (AD) is a common neurodegenerative disease with high incidence
among old people. Dioscin is a product extracted from natural herbs, which has multiple …

Enriched endogenous omega-3 polyunsaturated fatty acids protect cortical neurons from experimental ischemic injury

Z Shi, H Ren, C Luo, X Yao, P Li, C He, JX Kang… - Molecular …, 2016 - Springer
Omega-3 polyunsaturated fatty acids (n-3 PUFAs) exert therapeutic potential in a variety of
neurological disorders, including ischemic stroke. However, the underlying mechanisms still …