Modulating Vibrio cholerae Quorum-Sensing-Controlled Communication Using Autoinducer-Loaded Nanoparticles
The rise of bacterial antibiotic resistance has created a demand for alternatives to traditional
antibiotics. Attractive possibilities include pro-and anti-quorum sensing therapies that …
antibiotics. Attractive possibilities include pro-and anti-quorum sensing therapies that …
Technological strategies to estimate and control diffusive passage times through the mucus barrier in mucosal drug delivery
In mucosal drug delivery, two design goals are desirable: 1) insure drug passage through
the mucosal barrier to the epithelium prior to drug removal from the respective organ via …
the mucosal barrier to the epithelium prior to drug removal from the respective organ via …
Development of emulgel formulation for vaginal candidiasis: Pharmaceutical characterization, in vitro and in vivo evaluation
The aim of the investigation was to develop nanoemulsion (NE) based emulgel of Mentha
essential oil (MEO: potent antifungal property) to ensure enriched and extended therapeutic …
essential oil (MEO: potent antifungal property) to ensure enriched and extended therapeutic …
Microrheology for biomaterial design
Microrheology analyzes the microscopic behavior of complex materials by measuring the
diffusion and transport of embedded particle probes. This experimental method can provide …
diffusion and transport of embedded particle probes. This experimental method can provide …
[HTML][HTML] LPS-binding IgG arrests actively motile Salmonella Typhimurium in gastrointestinal mucus
HA Schroeder, J Newby, A Schaefer, B Subramani… - Mucosal …, 2020 - Elsevier
The gastrointestinal (GI) mucosa is coated with a continuously secreted mucus layer that
serves as the first line of defense against invading enteric bacteria. We have previously …
serves as the first line of defense against invading enteric bacteria. We have previously …
Mechanisms of carotenoid intestinal absorption and the regulation of dietary lipids: lipid transporter-mediated transintestinal epithelial pathways
Z Guo, Y Liu, Y Luo - Critical Reviews in Food Science and …, 2024 - Taylor & Francis
Dietary lipids are key ingredients during cooking, processing, and seasoning of carotenoid-
rich fruits and vegetables, playing vitals in affecting the absorption and utilization of …
rich fruits and vegetables, playing vitals in affecting the absorption and utilization of …
A review of mixing and propulsion of chyme in the small intestine: fresh insights from new methods
RG Lentle, C De Loubens - Journal of Comparative Physiology B, 2015 - Springer
The small intestine is a convoluted flexible tube of inconstant form and capacity through
which chyme is propelled and mixed by varying patterns of contraction. These inconstancies …
which chyme is propelled and mixed by varying patterns of contraction. These inconstancies …
Generating an In Vitro Gut Model with Physiologically Relevant Biophysical Mucus Properties
J McCright, A Sinha, K Maisel - Cellular and molecular bioengineering, 2022 - Springer
Introduction Gastrointestinal (GI) in vitro models have received lasting attention as an
effective tool to model drug and nutrient absorption, study GI diseases, and design new drug …
effective tool to model drug and nutrient absorption, study GI diseases, and design new drug …
Nanomedicine for Maternal and Fetal Health
Conception, pregnancy, and childbirth are complex processes that affect both mother and
fetus. Thus, it is perhaps not surprising that in the United States alone, roughly 11% of …
fetus. Thus, it is perhaps not surprising that in the United States alone, roughly 11% of …
Efficacy and safety concerns over the use of mucus modulating agents for drug delivery using nanoscale systems
PI Chater, MD Wilcox, JP Pearson - Advanced Drug Delivery Reviews, 2018 - Elsevier
Drug delivery to the mucus covered mucosae is fraught with difficulties and many different
approaches have been developed to permeate the mucus barrier. Generally by modifying …
approaches have been developed to permeate the mucus barrier. Generally by modifying …