Preterm birth (PTB)(< 37 weeks of gestation) is the second largest direct cause of mortality in
children under the age of five. Infants born preterm often have various medical …

Multiple particle tracking (MPT) is a technique that allows for individual particles to be traced
in complex biological matrices. It provides information on which formulations of …

Physiologically, mucosal systems occur in three different states–as membrane-tethered
surface layers, solutions, and hydrogels. In this thesis, models for these mucosal systems …

The nano-particulate colloidal aerosols by inhalation are used to improve the health of
human beings for many years. A wide variety of medicinal colloids has been administered to …

Efficient pharmacotherapy is mainly dependent on the effective localized delivery of
therapeutic agents to the targeted biological site. Many potent therapeutics exhibit …

Note: The Figure 1.1 in this chapter was originally published in Frontiers in Bioengineering
and Biotechnology: Lenzini S., Devine D., and Shin J.-W. Leveraging biomaterial mechanics …

L'administration de vaccins par voie muqueuse (orale et nasale) est une alternative efficace
aux injections classiques. En effet, au-delà d'une plus grande compliance pour les patients …

Lungs are an attractive target for the pulmonary administration of functional molecules due
to the large surface area for absorption, abundant blood circulation, better permeability, and …

A layer of mucus covers the surface of the pulmonary airways. Mucus is a hydrogel mainly
composed of water, mucins (glycoproteins), DNA, proteins, lipids, and cell debris, which …