The role of quality of life data as an endpoint for collecting real-world evidence within geroscience clinical trials

G Harinath, S Zalzala, A Nyquist, M Wouters… - Ageing Research …, 2024 - Elsevier
With geroscience research evolving at a fast pace, the need arises for human randomized
controlled trials to assess the efficacy of geroprotective interventions to prevent age-related …

[HTML][HTML] An Introductory Guide to Using Bloomington Drosophila Stock Center and FlyBase for Aging Research

X Zheng - Cells, 2024 - mdpi.com
Studies on numerous species have demonstrated strikingly conserved mechanisms that
determine the aging process, from yeasts to worms, flies, zebrafish, mice, and humans. The …

Exposure to residential green and blue space and the natural environment is associated with a lower incidence of psychiatric disorders in middle-aged and older …

BP Liu, RR Huxley, T Schikowski, KJ Hu, Q Zhao… - BMC medicine, 2024 - Springer
Background There is increasing evidence for the role of environmental factors and exposure
to the natural environment on a wide range of health outcomes. Whether exposure to green …

The association between weekly exercise patterns and acceleration of aging: Evidence from a population-based study

GY Jiang, W Zhang, H Kang, J Wang, Z Liu, Z Wang… - Preventive …, 2024 - Elsevier
Background Acceleration of aging is a major challenge in public health. Previous studies
have focused on the associations between specific types of exercise or overall levels of …

Heterogeneous metabolomic aging across the same age and prediction of health outcome

X Jia, J Fan, X Wu, X Cao, L Ma, Z Abdelrahman… - medRxiv, 2024 - medrxiv.org
Existing metabolomic clocks exhibit deficiencies in capturing the heterogeneous aging rates
among individuals with the same chronological age. Yet, the modifiable and non-modifiable …

Association between biological ageing and periodontitis: Evidence from a cross‐sectional survey and multi‐omics Mendelian randomization analysis

Z Huang, S Peng, T Cen, X Wang, L Ma… - Journal of Clinical … - Wiley Online Library
Aim To investigate the relationship and potential causality between biological ageing and
periodontitis. Materials and Methods We obtained the National Health and Nutrition …

Association between Frailty and Senescence from National Health and Nutrition Examination Survey (NHANES): A Cross-Sectional Study

RJ Xie, XJ Tian, M Meng, H Ma - 2023 - researchsquare.com
Background Aging is an inevitable phenomenon of biological processes, and frailty, one of
its key symptoms, usually reflects a decline in the body's functional and adaptive capacity. In …

[PDF][PDF] Omics-based prediction of human phenotypes using scalable machine learning approaches

MCC Moreno - 2024 - repositorio-aberto.up.pt
Omics-based prediction of human phenotypes using scalable machine learning approaches
Page 1 Omics-based prediction of human phenotypes using scalable machine learning …

Association between biological aging and Asthma-COPD overlap based on Nhanes 2005-2018

T Sun, S Yang, S Li, H Li, J Yu, J Wang - 2024 - researchsquare.com
BACKGROUND Aging is an important factor in the pathogenesis of various respiratory
diseases, and biological aging can better reflect the systemic functional status of individual …