[HTML][HTML] Gut microbiome in gastrointestinal cancer: a friend or foe?

Y Liu, Y Baba, T Ishimoto, X Gu, J Zhang… - … Journal of Biological …, 2022 - ncbi.nlm.nih.gov
The impact of the gut microbiome on host health is becoming increasingly recognized. To
date, there is growing evidence that the complex characteristics of the microbial community …

[HTML][HTML] Focus on immune checkpoint PD-1/PD-L1 pathway: New advances of polyphenol phytochemicals in tumor immunotherapy

K Liu, Q Sun, Q Liu, H Li, W Zhang, C Sun - Biomedicine & …, 2022 - Elsevier
The rise of cancer immunotherapy, particularly the use of immune checkpoint inhibitors
(ICIs), has significantly changed the clinical treatment paradigm for patients with cancer. The …

A novel pH‐responsive nanoniosomal emulsion for sustained release of curcumin from a chitosan‐based nanocarrier: emphasis on the concurrent improvement of …

S Haseli, M Pourmadadi, A Samadi… - Biotechnology …, 2022 - Wiley Online Library
Curcumin application as an anti‐cancer drug is faced with several impediments. This study
has developed a platform that facilitates the sustained release of curcumin, improves …

The multifaceted role of flavonoids in cancer therapy: leveraging autophagy with a double-edged sword

Z Zhang, J Shi, EC Nice, C Huang, Z Shi - Antioxidants, 2021 - mdpi.com
Flavonoids are considered as pleiotropic, safe, and readily obtainable molecules. A large
number of recent studies have proposed that flavonoids have potential in the treatment of …

[HTML][HTML] The interplay of arsenic, silymarin, and NF-ĸB pathway in male reproductive toxicity: A review

AG Mukherjee, AV Gopalakrishnan - Ecotoxicology and Environmental …, 2023 - Elsevier
Arsenic toxicity is one of the most trending reasons for several malfunctions, particularly
reproductive toxicity. The exact mechanism of arsenic poisoning is a big question mark …

Boosting curcumin activity against human prostatic cancer PC3 cells by utilizing scorpion venom conjugated phytosomes as promising functionalized nanovesicles

MW Al-Rabia, NA Alhakamy, WY Rizg, AF Alghaith… - Drug Delivery, 2022 - Taylor & Francis
Prostate cancer (PC) is emerging as one of the leading causes of mortality and morbidity
worldwide. Curcumin (CUR) is a well-known phytochemical, and scorpion venom (SV) is a …

Chiral flavonoids as antitumor agents

C Pinto, H Cidade, M Pinto, ME Tiritan - Pharmaceuticals, 2021 - mdpi.com
Flavonoids are a group of natural products with a great structural diversity, widely distributed
in plant kingdom. They play an important role in plant growth, development and defense …

Phytochemicals for the prevention and treatment of renal cell carcinoma: preclinical and clinical evidence and molecular mechanisms

EM Bajalia, FB Azzouz, DA Chism, DM Giansiracusa… - Cancers, 2022 - mdpi.com
Simple Summary Renal cell carcinoma (RCC) is the most frequently diagnosed kidney
cancer. Once RCC metastasizes, successful treatment is difficult to achieve. There is an …

[HTML][HTML] Bioactive compounds from nature: Antioxidants targeting cellular transformation in response to epigenetic perturbations induced by oxidative stress

A Bouyahya, S Bakrim, S Aboulaghras… - Biomedicine & …, 2024 - Elsevier
Oxidative stress results from a persistent imbalance in oxidation levels that promotes
oxidants, playing a crucial role in the early and sustained phases of DNA damage and …

Advances in mitophagy and mitochondrial apoptosis pathway-related drugs in glioblastoma treatment

W Li, X Xu - Frontiers in Pharmacology, 2023 - frontiersin.org
Glioblastoma (GBM) is the most common malignant tumor of the central nervous system
(CNS). It is a leading cause of death among patients with intracranial malignant tumors …