[HTML][HTML] The Angelica dahurica: A Review of Traditional Uses, Phytochemistry and Pharmacology

H Zhao, YL Feng, M Wang, JJ Wang, T Liu… - Frontiers in …, 2022 - frontiersin.org
Angelica dahurica (A. dahurica) root is a famous edible medicinal herb that has been used
in China for thousands of years. To date, more than 300 chemical constituents have been …

[HTML][HTML] The potential application of chinese medicine in liver diseases: a new opportunity

K Fu, C Wang, C Ma, H Zhou, Y Li - Frontiers in Pharmacology, 2021 - frontiersin.org
Liver diseases have been a common challenge for people all over the world, which
threatens the quality of life and safety of hundreds of millions of patients. China is a major …

Protective effect of Que Zui tea hot-water and aqueous ethanol extract against acetaminophen-induced liver injury in mice via inhibition of oxidative stress …

Y Wang, L Tian, Y Wang, T Zhao, A Khan, Y Wang… - Food & Function, 2021 - pubs.rsc.org
The tender leaves and buds of Vaccinium dunalianum Wight have been traditionally
processed as folk tea, known as Que Zui tea (QT), with a wide range of benefits to humans …

[HTML][HTML] Imperatorin positively regulates melanogenesis through signaling pathways involving Pka/Creb, Erk, Akt, and Gsk3β/Β-catenin

T Kim, CG Hyun - Molecules, 2022 - mdpi.com
The present study investigated the melanogenic effects of imperatorin and isoimperatorin
and the underlying mechanisms of imperatorin using a mouse melanoma B16F10 model …

[HTML][HTML] Preventive effects of mandarin fruit peel hydroethanolic extract, hesperidin, and quercetin on acetaminophen-induced hepatonephrotoxicity in Wistar rats

DN Eldin, HI Fahim, HY Ahmed… - … Medicine and Cellular …, 2022 - hindawi.com
Acetaminophen, also known as N-acetyl-para-aminophenol (NAPAP), is a traditional
antipyretic and analgesic that is used extensively around the world to treat colds and fevers …

Protective effect and mechanism of chitooligosaccharides on acetaminophen-induced liver injury

J Xiang, J Wang, H Xie, Y Liu, Y Bai, Q Che, H Cao… - Food & Function, 2021 - pubs.rsc.org
Currently, drug-induced liver injury caused by acetaminophen (APAP) is the second leading
cause of human liver transplantation. The only clinical antidote treatment for APAP-induced …

[HTML][HTML] The immunological mechanisms and therapeutic potential in drug-induced liver injury: Lessons learned from acetaminophen hepatotoxicity

Q Li, F Chen, F Wang - Cell & Bioscience, 2022 - Springer
Acute liver failure caused by drug overdose is a significant clinical problem in developed
countries. Acetaminophen (APAP), a widely used analgesic and antipyretic drug, but its …

[HTML][HTML] SIRT1 activation synergizes with FXR agonism in hepatoprotection via governing nucleocytoplasmic shuttling and degradation of FXR

S Cui, H Hu, A Chen, M Cui, X Pan, P Zhang… - … Pharmaceutica Sinica B, 2023 - Elsevier
Farnesoid X receptor (FXR) is widely accepted as a promising target for various liver
diseases; however, panels of ligands in drug development show limited clinical benefits …

[HTML][HTML] Gut microbiota accelerates cisplatin-induced acute liver injury associated with robust inflammation and oxidative stress in mice

S Gong, Y Feng, Y Zeng, H Zhang, M Pan, F He… - Journal of translational …, 2021 - Springer
Background Gut microbiota has been reported to be disrupted by cisplatin, as well as to
modulate chemotherapy toxicity. However, the precise role of intestinal microbiota in the …

[HTML][HTML] Paeoniflorin protects against ANIT-induced cholestatic liver injury in rats via the activation of SIRT1-FXR signaling pathway

L Chen, S Wei, H Liu, J Li, M Jing, Y Tong… - Evidence-Based …, 2021 - hindawi.com
Paeoniflorin (PF), a water-soluble monoterpene glycoside, is initially isolated from the dried
roots of Paeonia lactiflora Pall., which has effects on ameliorating cholestasis in our previous …