[HTML][HTML] Recent advances in therapeutic applications of neutralizing antibodies for virus infections: an overview

MG Ali, Z Zhang, Q Gao, M Pan, EG Rowan… - Immunologic …, 2020 - Springer
Antibodies are considered as an excellent foundation to neutralize pathogens and as highly
specific therapeutic agents. Antibodies are generated in response to a vaccine but little use …

[HTML][HTML] Improving the efficacy of regulatory T cell therapy

P Baeten, L Van Zeebroeck, M Kleinewietfeld… - Clinical reviews in …, 2022 - Springer
Autoimmunity is caused by an unbalanced immune system, giving rise to a variety of organ-
specific to system disorders. Patients with autoimmune diseases are commonly treated with …

[HTML][HTML] Crosstalk between nucleocytoplasmic trafficking and the innate immune response to viral infection

Q Shen, YE Wang, AF Palazzo - Journal of Biological Chemistry, 2021 - ASBMB
The nuclear pore complex is the sole gateway connecting the nucleoplasm and cytoplasm.
In humans, the nuclear pore complex is one of the largest multiprotein assemblies in the cell …

[HTML][HTML] Immunesenescence: a predisposing risk factor for the development of COVID-19?

J Hazeldine, JM Lord - Frontiers in immunology, 2020 - frontiersin.org
Bearing a strong resemblance to the phenotypic and functional remodeling of the immune
system that occurs during aging (termed immunesenescence), the immune response to …

SARS-CoV-2/COVID-19: evolving reality, global response, knowledge gaps, and opportunities

MF Osuchowski, F Aletti, JM Cavaillon, SB Flohe… - Shock, 2020 - journals.lww.com
Approximately 3 billion people around the world have gone into some form of social
separation to mitigate the current severe acute respiratory syndrome coronavirus 2 (SARS …

Evaluating fluvoxamine for the outpatient treatment of COVID‐19: A systematic review and meta‐analysis

J Deng, M Moskalyk, QK Zuo, C Garcia… - Reviews in Medical …, 2024 - Wiley Online Library
This systematic review and meta‐analysis of randomised controlled trials (RCTs) aimed to
evaluate the efficacy, safety, and tolerability of fluvoxamine for the outpatient management of …

[HTML][HTML] Neutrophil-to-lymphocyte ratios are closely associated with the severity and course of non-mild COVID-19

S Qun, Y Wang, J Chen, X Huang, H Guo, Z Lu… - Frontiers in …, 2020 - frontiersin.org
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is
spreading worldwide. Measuring the prevention and control of the disease has become a …

SARS-CoV-2 attachment to host cells is possibly mediated via RGD-integrin interaction in a calcium-dependent manner and suggests pulmonary EDTA chelation …

TC Dakal - Immunobiology, 2021 - Elsevier
SARS-CoV-2 is a highly contagious virus that has caused serious health crisis world-wide
resulting into a pandemic situation. As per the literature, the SARS-CoV-2 is known to exploit …

COVID‐19 immunopathology with emphasis on Th17 response and cell‐based immunomodulation therapy: potential targets and challenges

A Pourgholaminejad… - Scandinavian Journal …, 2022 - Wiley Online Library
The role of the immune system against coronavirus disease 2019 (COVID‐19) is unknown in
many aspects, and the protective or pathologic mechanisms of the immune response are …

[HTML][HTML] A Randomized, Single-blind, Group sequential, Active-controlled Study to evaluate the clinical efficacy and safety of α-Lipoic acid for critically ill patients with …

M Zhong, A Sun, T Xiao, G Yao, L Sang, X Zheng… - Frontiers in …, 2022 - frontiersin.org
Object To evaluate the clinical efficacy and safety of α-Lipoic acid (ALA) for critically ill
patients with coronavirus disease 2019 (COVID-19). Methods A randomized, single-blind …