BRCA mutations in ovarian and prostate cancer: bench to bedside
Simple Summary DNA damage is one of the hallmarks of cancer. Epithelial ovarian cancer
(EOC)—especially the high-grade serous subtype—harbors a defect in at least one DNA …
(EOC)—especially the high-grade serous subtype—harbors a defect in at least one DNA …
Chronic inflammation and radiation-induced cystitis: molecular background and therapeutic perspectives
C Helissey, S Cavallero, C Brossard, M Dusaud… - Cells, 2020 - mdpi.com
Radiation cystitis is a potential complication following the therapeutic irradiation of pelvic
cancers. Its clinical management remains unclear, and few preclinical data are available on …
cancers. Its clinical management remains unclear, and few preclinical data are available on …
Therapy-induced modulation of the tumor microenvironment: new opportunities for cancer therapies
S Benavente, A Sánchez-García, S Naches… - Frontiers in …, 2020 - frontiersin.org
Advances in immunotherapy have achieved remarkable clinical outcomes in tumors with low
curability, but their effects are limited, and increasing evidence has implicated tumoral and …
curability, but their effects are limited, and increasing evidence has implicated tumoral and …
Radiotherapy in bone sarcoma: the quest for better treatment option
MA Locquet, M Brahmi, JY Blay, A Dutour - BMC cancer, 2023 - Springer
Bone sarcomas are rare tumors representing 0.2% of all cancers. While osteosarcoma and
Ewing sarcoma mainly affect children and young adults, chondrosarcoma and chordoma …
Ewing sarcoma mainly affect children and young adults, chondrosarcoma and chordoma …
[HTML][HTML] High incidence combination of multiple primary malignant tumors of the digestive system
XB Yang, LH Zhang, JN Xue, YC Wang… - World Journal of …, 2022 - ncbi.nlm.nih.gov
BACKGROUND Clinical reports of multiple primary malignant tumors (MPMTs) in the
digestive system are increasing. In China, although the survival rate of patients with MPMTs …
digestive system are increasing. In China, although the survival rate of patients with MPMTs …
Impact of radiation therapy on healthy tissues
C Chargari, E Rassy, C Helissey, S Achkar… - International review of …, 2023 - Elsevier
Radiation therapy has a fundamental role in the management of cancers. However, despite
a constant improvement in radiotherapy techniques, the issue of radiation-induced side …
a constant improvement in radiotherapy techniques, the issue of radiation-induced side …
Vulvar carcinoma: Standard of care and perspectives
C Chargari, J Wasserman, A Gabro… - Journal of Clinical …, 2024 - ascopubs.org
PURPOSE Treatment of vulvar carcinoma (VC) is challenging. The objectives of this review
were to describe for clinicians the epidemiologic and clinical aspects of VC, the standard of …
were to describe for clinicians the epidemiologic and clinical aspects of VC, the standard of …
Practice changing data and emerging concepts from recent radiation therapy randomised clinical trials
S Espenel, C Chargari, P Blanchard, S Bockel… - European Journal of …, 2022 - Elsevier
Introduction Oncology treatments are constantly and rapidly evolving. We aimed at
highlighting the latest radiation therapy practice changing trials and emerging concepts …
highlighting the latest radiation therapy practice changing trials and emerging concepts …
[HTML][HTML] Tumour motion management in lung cancer: a narrative review
A Botticella, A Levy, G Auzac, I Chabert… - Translational Lung …, 2021 - ncbi.nlm.nih.gov
Respiratory motion is one of the geometrical uncertainties that may affect the accuracy of
thoracic radiotherapy in the treatment of lung cancer. Accounting for tumour motion may …
thoracic radiotherapy in the treatment of lung cancer. Accounting for tumour motion may …
Immunologic effects of stereotactic body radiotherapy in dogs with spontaneous tumors and the impact of intratumoral OX40/TLR agonist immunotherapy
Stereotactic body radiotherapy (SBRT) is known to induce important immunologic changes
within the tumor microenvironment (TME). However, little is known regarding the early …
within the tumor microenvironment (TME). However, little is known regarding the early …