Novel approaches to target the microenvironment of bone metastasis

LC Hofbauer, A Bozec, M Rauner, F Jakob… - Nature reviews Clinical …, 2021 - nature.com
Bone metastases are a frequent and severe complication of advanced-stage cancers. Breast
and prostate cancers, the most common malignancies in women and men, respectively …

Molecular mechanisms of exercise contributing to tissue regeneration

J Chen, R Zhou, Y Feng, L Cheng - Signal Transduction and Targeted …, 2022 - nature.com
Physical activity has been known as an essential element to promote human health for
centuries. Thus, exercise intervention is encouraged to battle against sedentary lifestyle …

Piezo channels: awesome mechanosensitive structures in cellular mechanotransduction and their role in bone

X Xu, S Liu, H Liu, K Ru, Y Jia, Z Wu, S Liang… - International Journal of …, 2021 - mdpi.com
Piezo channels are mechanosensitive ion channels located in the cell membrane and
function as key cellular mechanotransducers for converting mechanical stimuli into …

[PDF][PDF] Biomanufacturing in low Earth orbit for regenerative medicine

A Sharma, RA Clemens, O Garcia, DL Taylor… - Stem Cell Reports, 2022 - cell.com
Research in low Earth orbit (LEO) has become more accessible. The 2020
Biomanufacturing in Space Symposium reviewed space-based regenerative medicine …

Role of physical activity in bone–muscle crosstalk: Biological aspects and clinical implications

I Cariati, R Bonanni, F Onorato… - Journal of functional …, 2021 - mdpi.com
Bone and muscle tissues influence each other through the integration of mechanical and
biochemical signals, giving rise to bone–muscle crosstalk. They are also known to secrete …

Changes in interstitial fluid flow, mass transport and the bone cell response in microgravity and normogravity

F Wei, K Flowerdew, M Kinzel, LE Perotti, J Asiatico… - Bone Research, 2022 - nature.com
In recent years, our scientific interest in spaceflight has grown exponentially and resulted in
a thriving area of research, with hundreds of astronauts spending months of their time in …

Myoblast-derived exosomal Prrx2 attenuates osteoporosis via transcriptional regulation of lncRNA-MIR22HG to activate Hippo pathway

Y Li, X Wang, C Pan, H Yuan, X Li, Z Chen, H He - Molecular Medicine, 2023 - Springer
Background Sarcopenia and osteoporosis are common diseases that predominantly affect
older individuals. The interaction between muscle and skeleton exerts pivotal roles in bone …

A bidirectional mendelian randomization study of sarcopenia-related traits and knee osteoarthritis

L Zhang, C Zhang, J Zhang, A Liu… - Clinical Interventions in …, 2023 - Taylor & Francis
Background With the development of population aging worldwide, sarcopenia and knee
osteoarthritis (KOA), two age-related diseases, will continue to impose increasing medical …

Recent advances in adhesive materials used in the biomedical field: Adhesive properties, mechanism, and applications

Y Lu, X Xu, J Li - Journal of Materials Chemistry B, 2023 - pubs.rsc.org
Adhesive materials are natural or synthetic polymers with the ability to adhere to the surface
of luminal mucus or epithelial cells. They are widely used in the biomedical field due to their …

[HTML][HTML] Magnetic resonance imaging techniques for the quantitative analysis of skeletal muscle: State of the art

K Engelke, O Chaudry, L Gast, MAB Eldib… - Journal of Orthopaedic …, 2023 - Elsevier
Background Magnetic resonance imaging (MRI) is the dominant 3D imaging modality to
quantify muscle properties in skeletal muscle disorders, in inherited and acquired muscle …