The Anti-Inflammatory Properties of Licorice (Glycyrrhiza glabra)-Derived Compounds in Intestinal Disorders

CS Leite, GA Bonafé, J Carvalho Santos… - International journal of …, 2022 - mdpi.com
Intestinal diseases, such as inflammatory bowel diseases (IBDs) and colorectal cancer
(CRC), are a significant source of morbidity and mortality worldwide. Epidemiological data …

Natural products for the prevention and treatment of oral mucositis—a review

AS Ferreira, C Macedo, AM Silva… - International Journal of …, 2022 - mdpi.com
Cancer, a major world public health problem, is associated with chemotherapy treatments
whose administration leads to secondary concerns, such as oral mucositis (OM). The OM …

Pro-inflammatory signalling PRRopels cisplatin-induced toxicity

IK Domingo, A Latif, AP Bhavsar - International journal of molecular …, 2022 - mdpi.com
Cisplatin is a platinum-based chemotherapeutic that has long since been effective against a
variety of solid-cancers, substantially improving the five-year survival rates for cancer …

[HTML][HTML] Revisiting liquorice (Glycyrrhiza glabra L.) as anti-inflammatory, antivirals and immunomodulators: Potential pharmacological applications with mechanistic …

D Bisht, M Rashid, RKK Arya, D Kumar… - Phytomedicine Plus, 2022 - Elsevier
Abstract Background Glycyrrhiza glabra L.(G. glabra) commonly known as liquorice is one of
the highly exploited and utilized medicinal plant of the world. Since ancient times liquorice is …

The role of HMGB1 in COVID‐19‐induced cytokine storm and its potential therapeutic targets: A review

S Wulandari, Hartono, T Wibawa - Immunology, 2023 - Wiley Online Library
Hyperinflammation characterized by elevated proinflammatory cytokines known as 'cytokine
storms' is the major cause of high severity and mortality seen in COVID‐19 patients. The …

[HTML][HTML] Glycyrrhetinic acid regulates impaired macrophage autophagic flux in the treatment of non-alcoholic fatty liver disease

Y Fan, W Dong, Y Wang, S Zhu, R Chai, Z Xu… - Frontiers in …, 2022 - frontiersin.org
Macrophages are involved in hepatocyte steatosis and necroinflammation and play an
important role in the pathogenesis of non-alcoholic fatty liver disease (NAFLD). Impaired …

A review of the antiviral activities of glycyrrhizic acid, glycyrrhetinic acid and glycyrrhetinic acid monoglucuronide

J Zuo, T Meng, Y Wang, W Tang - Pharmaceuticals, 2023 - mdpi.com
Licorice, a natural medicine derived from the roots and rhizomes of Glycyrrhiza species,
possesses a wide range of therapeutic applications, including antiviral properties …

Progress in traditional Chinese medicine against respiratory viruses: a review

BH Li, ZY Li, MM Liu, JZ Tian, QH Cui - Frontiers in Pharmacology, 2021 - frontiersin.org
Respiratory viruses, such as severe acute respiratory syndrome coronavirus (SARS-CoV)-1,
SARS-CoV-2, influenza A viruses, and respiratory syncytial virus, pose a serious threat to …

Glycyrrhetinic acid derivatives as Zika virus inhibitors: Synthesis and antiviral activity in vitro

LA Baltina, HC Lai, YC Liu, SH Huang, MJ Hour… - Bioorganic & Medicinal …, 2021 - Elsevier
Zika virus (ZIKV) is an arbovirus of the Flaviviridae family (Flavivirus genus), causing serious
neurological complications, such as Guillain-Barre Syndrome (GBS) in adults and fetal …

[HTML][HTML] Understanding immune-modulatory efficacy in vitro

S Khatua, J Simal-Gandara, K Acharya - Chemico-Biological Interactions, 2022 - Elsevier
Boosting or suppressing our immune system represents an attractive adjunct in the
treatment of infections including SARS-CoV-2, cancer, AIDS, malnutrition, age related …