Autoimmune diseases are a diverse group of conditions characterized by aberrant B cell
and T cell reactivity to normal constituents of the host. These diseases occur widely and …

The discovery of genotype 16 as the prototype oncogenic human papillomavirus (HPV)
initiated a quarter century of laboratory and epidemiological studies that demonstrated their …

Background Whereas severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-
specific antibody tests are increasingly being used to estimate the prevalence of SARS-CoV …

Plasma cells (PC) are found in the CNS of multiple sclerosis (MS) patients, yet their source
and role in MS remains unclear. We find that some PC in the CNS of mice with experimental …

Abstract Background Most SARS-CoV-2 infected patients develop IgG antibodies within 2–3
weeks after symptom onset. Antibody levels have been shown to gradually decrease in the …

Immunological memory is a mechanism to protect us against reinfection. Antibodies
produced by B cells are integral to this defense strategy and underlie virtually all vaccine …

Antibody responses to viral infections are sustained for decades by long-lived plasma cells
(LLPCs). However, LLPCs have yet to be characterized in humans. Here we used CD19 …

Perreault and colleagues examined antibody titers in sequential samples from serum donors
recovering from COVID-19 and demonstrated that antibody titers fall over 3-4 months. These …

SARS-CoV-2 variants that attenuate antibody neutralization could jeopardize vaccine
efficacy. We recently reported the protective activity of an intranasally administered spike …

Summary Background The RTS, S/AS01 malaria vaccine targets the circumsporozoite
protein, inducing antibodies associated with the prevention of Plasmodium falciparum …