Pathogenesis of autoimmune disease
DS Pisetsky - Nature Reviews Nephrology, 2023 - nature.com
Autoimmune diseases are a diverse group of conditions characterized by aberrant B cell
and T cell reactivity to normal constituents of the host. These diseases occur widely and …
and T cell reactivity to normal constituents of the host. These diseases occur widely and …
[HTML][HTML] Opportunities and challenges for human papillomavirus vaccination in cancer
R Roden, PL Stern - Nature Reviews Cancer, 2018 - nature.com
The discovery of genotype 16 as the prototype oncogenic human papillomavirus (HPV)
initiated a quarter century of laboratory and epidemiological studies that demonstrated their …
initiated a quarter century of laboratory and epidemiological studies that demonstrated their …
Systemic and mucosal antibody responses specific to SARS-CoV-2 during mild versus severe COVID-19
Background Whereas severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-
specific antibody tests are increasingly being used to estimate the prevalence of SARS-CoV …
specific antibody tests are increasingly being used to estimate the prevalence of SARS-CoV …
[HTML][HTML] Recirculating intestinal IgA-producing cells regulate neuroinflammation via IL-10
OL Rojas, AK Pröbstel, EA Porfilio, AA Wang… - Cell, 2019 - cell.com
Plasma cells (PC) are found in the CNS of multiple sclerosis (MS) patients, yet their source
and role in MS remains unclear. We find that some PC in the CNS of mice with experimental …
and role in MS remains unclear. We find that some PC in the CNS of mice with experimental …
Longitudinal follow-up of IgG anti-nucleocapsid antibodies in SARS-CoV-2 infected patients up to eight months after infection
J Van Elslande, M Oyaert, S Ailliet, M Van Ranst… - Journal of Clinical …, 2021 - Elsevier
Abstract Background Most SARS-CoV-2 infected patients develop IgG antibodies within 2–3
weeks after symptom onset. Antibody levels have been shown to gradually decrease in the …
weeks after symptom onset. Antibody levels have been shown to gradually decrease in the …
[HTML][HTML] B cell memory: understanding COVID-19
I Quast, D Tarlinton - Immunity, 2021 - cell.com
Immunological memory is a mechanism to protect us against reinfection. Antibodies
produced by B cells are integral to this defense strategy and underlie virtually all vaccine …
produced by B cells are integral to this defense strategy and underlie virtually all vaccine …
Long-lived plasma cells are contained within the CD19− CD38hiCD138+ subset in human bone marrow
JL Halliley, CM Tipton, J Liesveld, AF Rosenberg… - Immunity, 2015 - cell.com
Antibody responses to viral infections are sustained for decades by long-lived plasma cells
(LLPCs). However, LLPCs have yet to be characterized in humans. Here we used CD19 …
(LLPCs). However, LLPCs have yet to be characterized in humans. Here we used CD19 …
Waning of SARS-CoV-2 RBD antibodies in longitudinal convalescent plasma samples within 4 months after symptom onset
J Perreault, T Tremblay, MJ Fournier… - Blood, The Journal …, 2020 - ashpublications.org
Perreault and colleagues examined antibody titers in sequential samples from serum donors
recovering from COVID-19 and demonstrated that antibody titers fall over 3-4 months. These …
recovering from COVID-19 and demonstrated that antibody titers fall over 3-4 months. These …
[HTML][HTML] An intranasal vaccine durably protects against SARS-CoV-2 variants in mice
SARS-CoV-2 variants that attenuate antibody neutralization could jeopardize vaccine
efficacy. We recently reported the protective activity of an intranasally administered spike …
efficacy. We recently reported the protective activity of an intranasally administered spike …
Immunogenicity of the RTS, S/AS01 malaria vaccine and implications for duration of vaccine efficacy: secondary analysis of data from a phase 3 randomised …
Summary Background The RTS, S/AS01 malaria vaccine targets the circumsporozoite
protein, inducing antibodies associated with the prevention of Plasmodium falciparum …
protein, inducing antibodies associated with the prevention of Plasmodium falciparum …