Development of nanoparticles for pharmaceutical preparations using supercritical techniques

T Islam, A Al Ragib, S Ferdosh… - Chemical …, 2022 - Taylor & Francis
This review focuses on nanoparticle (NP) synthesis and particle size design using
supercritical fluid (SCF) technology for pharmaceutical formulations. SCF technology is seen …

Precipitation of resveratrol-isoniazid and resveratrol-nicotinamide cocrystals by gas antisolvent

AS Pessoa, GPS Aguiar, JV Oliveira… - The Journal of …, 2019 - Elsevier
Over the last years, resveratrol (RES), a phytoalexin found in grape skin, has received more
attention due to its properties antioxidant, anticancer, anti-inflammatory, antimicrobial and …

Curcumin-nicotinamide cocrystallization with supercritical solvent (CSS): Synthesis, characterization and in vivo antinociceptive and anti-inflammatory activities

MM Ribas, GPS Aguiar, LG Muller, AM Siebel… - Industrial Crops and …, 2019 - Elsevier
Curcumin is a bioactive polyphenol, which presents several medicinal benefits such as
antinociceptive, anti-inflammatory, anti-carcinogenic, antimalarial, and antioxidant activity …

Production of curcumin-resveratrol cocrystal using cocrystallization with supercritical solvent

C Dal Magro, AE dos Santos, MM Ribas… - The Journal of …, 2021 - Elsevier
Bioactive compounds curcumin and resveratrol have been appointed to have potential for
prevention and treatment of several diseases, replacing synthetic compounds with limited …

[HTML][HTML] Micronization potentiates curcumin's anti-seizure effect and brings an important advance in epilepsy treatment

KT Bertoncello, GPS Aguiar, JV Oliveira, AM Siebel - Scientific reports, 2018 - nature.com
Epilepsy is one of the most common neurological diseases, and current antiepileptic drugs
fail to suppress seizure occurrence in around one third of epileptic patients. Curcumin is a …

Micronization of trans-resveratrol by supercritical fluid: Dissolution, solubility and in vitro antioxidant activity

GPS Aguiar, BD Arcari, LMPC Chaves… - Industrial Crops and …, 2018 - Elsevier
The micronization process is characterized by the reduction of particle size towards
obtaining changes in physical structure and increase the dissolution rate, which leads to …

Encapsulation of olive leaf (Olea europaea) extract using solution-enhanced dispersion by supercritical fluids (SEDS) technique

A Dalla Rosa, MC Secco, AM De Cezaro… - The Journal of …, 2023 - Elsevier
Olive leaves are considered a byproduct or agroindustry waste, although they contain
several bioactive compounds. The objective of this work was to encapsulate olive leaf …

Ultrasound-assisted emulsion of laurel leaves essential oil (Laurus nobilis L.) encapsulated by SFEE

PMCL Reis, N Mezzomo, GPS Aguiar… - The Journal of …, 2019 - Elsevier
Essential oil of laurel leaves presents, as the main component, the bioactive 1, 8-cineole.
The Supercritical Fluid Extraction of Emulsions (SFEE) is an alternative method for the …

Curcumin cocrystals using supercritical fluid technology

MM Ribas, GSB Sakata, AE Santos… - The Journal of …, 2019 - Elsevier
Cocrystallization is a method that enables an improvement in physicochemical properties
such as solubility, bioavailability, dissolution rate and stability. Curcumin (CUR) is bioactive …

Curcumin micronization by supercritical fluid: In vitro and in vivo biological relevance

A Sachett, M Gallas-Lopes, R Benvenutti… - Industrial Crops and …, 2022 - Elsevier
Curcumin, a polyphenol extracted from the rhizome of Curcuma longa L.(Zingiberaceae), is
shown to have antioxidant, anti-inflammatory, neuroprotective, anxiolytic, and …