Middle East respiratory syndrome and severe acute respiratory syndrome: current therapeutic options and potential targets for novel therapies

J Dyall, R Gross, J Kindrachuk, RF Johnson… - Drugs, 2017 - Springer
No specific antivirals are currently available for two emerging infectious diseases, Middle
East respiratory syndrome (MERS) and severe acute respiratory syndrome (SARS). A …

Viral infection in community-acquired pneumonia: a systematic review and meta-analysis

M Burk, K El-Kersh, M Saad, T Wiemken… - European …, 2016 - Eur Respiratory Soc
The advent of PCR has improved the identification of viruses in patients with community-
acquired pneumonia (CAP). Several studies have used PCR to establish the importance of …

In vitro virucidal activity of Echinaforce®, an Echinacea purpurea preparation, against coronaviruses, including common cold coronavirus 229E and SARS-CoV-2

J Signer, HR Jonsdottir, WC Albrich, M Strasser, R Züst… - Virology journal, 2020 - Springer
Abstract Background Coronaviruses (CoVs) were long thought to only cause mild respiratory
and gastrointestinal symptoms in humans but outbreaks of Middle East Respiratory …

Systematic review of respiratory viral pathogens identified in adults with community-acquired pneumonia in Europe

Y Alimi, WS Lim, L Lansbury, J Leonardi-Bee… - Journal of Clinical …, 2017 - Elsevier
Community-acquired pneumonia (CAP) is an important respiratory disease and the fifth
leading cause of mortality in Europe. The development of molecular diagnostic tests has …

Update on nitazoxanide: a multifunctional chemotherapeutic agent

A Shakya, HR Bhat, SK Ghosh - Current drug discovery …, 2018 - ingentaconnect.com
Background: The thiazolide nitazoxanide (NTZ) is a broad-spectrum antiinfective drug that
adversely affects viability, growth, and proliferation of a range of extracellular and …

Respiratory RNA viruses

RL Hodinka - Diagnostic Microbiology of the …, 2016 - Wiley Online Library
Viruses account for more episodes of respiratory tract disease than any other microbial
pathogens, and exact a significant toll on society and healthcare systems, leading to …

New therapeutic targets for the prevention of infectious acute exacerbations of COPD: role of epithelial adhesion molecules and inflammatory pathways

B Atto, MS Eapen, P Sharma, U Frey, AJ Ammit… - Clinical …, 2019 - portlandpress.com
Chronic respiratory diseases are among the leading causes of mortality worldwide, with the
major contributor, chronic obstructive pulmonary disease (COPD) accounting for …

The impact of influenza virus infection in pregnancy

LK Somerville, K Basile, DE Dwyer, J Kok - Future microbiology, 2018 - Taylor & Francis
Data from previous seasonal epidemics and pandemics have confirmed that pregnant
women are at increased risk for severe influenza virus infection. Complications including …

Mass gatherings and the spread of respiratory infections. Lessons from the Hajj

JA Al-Tawfiq, P Gautret, S Benkouiten… - Annals of the American …, 2016 - atsjournals.org
The mass gathering of people is a potential source for developing, propagating, and
disseminating infectious diseases on a global scale. Of the illnesses associated with mass …

Impact of respiratory virus infections in exacerbation of acute and chronic rhinosinusitis

KS Tan, Y Yan, HH Ong, VTK Chow, L Shi… - Current allergy and …, 2017 - Springer
Rhinosinusitis (RS) is a symptomatic disease classification of many causes and is a major
economic burden worldwide. It is widely accepted that RS is further classified into acute …